Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50045100
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50161764(CHEMBL177611 | (R)-4-chloro-N-(quinuclidin-3-yl)be...)
Affinity DataKi:  26nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50045045(CHEMBL3341965)
Affinity DataKi: >300nMAssay Description:Partial agonist activity at rat alpha6 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50045045(CHEMBL3341965)
Affinity DataKi: >300nMAssay Description:Partial agonist activity at rat alpha7 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50045044(CHEMBL3341967)
Affinity DataKi:  399nMAssay Description:Partial agonist activity at alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50048392(BUPROPION HYDROCHLORIDE | CHEMBL894 | 2-(tert-buty...)
Affinity DataIC50: 550nMAssay Description:Inhibition of DAT (unknown origin) assessed as transporter-mediated dopamine reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50161764(CHEMBL177611 | (R)-4-chloro-N-(quinuclidin-3-yl)be...)
Affinity DataKi:  930nMAssay Description:Inhibition of 5-HT3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50045044(CHEMBL3341967)
Affinity DataKi:  944nMAssay Description:Partial agonist activity at alpha1 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50045047(Dexmecamylamine | TC-5214)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at human alpha7 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50045046(CHEMBL3341962)
Affinity DataIC50: 1.60E+3nMAssay Description:Non-competitive antagonist activity at alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50369323(MECAMYLAMINE)
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at human alpha7 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143282((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  5.89E+3nMAssay Description:Partial agonist activity at alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50048392(BUPROPION HYDROCHLORIDE | CHEMBL894 | 2-(tert-buty...)
Affinity DataIC50: 7.90E+3nMAssay Description:Non-competitive antagonist activity at alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed