Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50045108
TargetPeptidyl-prolyl cis-trans isomerase FKBP1B(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM36609(Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, ...)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to FKBP12 (unknown origin) by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)
Affinity DataKd:  11nMAssay Description:Binding affinity to p38alpha MAP kinase (unknown origin) by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50130950(CHEMBL310759 | 5-[(4-chlorophenyl)sulfanyl]quinazo...)
Affinity DataKd:  120nMAssay Description:Binding affinity to DHFR (unknown origin) by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetGalectin-3(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  2.30E+5nMAssay Description:Binding affinity to galectin-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetGalectin-3(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50045334(CHEMBL3337492)
Affinity DataKd:  1.82E+4nMAssay Description:Binding affinity to galectin-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetGalectin-3(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50045335(CHEMBL3337493)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to galectin-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target6-phosphogluconolactonase(Trypanosoma brucei)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50045357(CHEBI:48928 | CHEMBL1230513)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to Trypanosoma brucei 6-phospho-gluconalactonase by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1B(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50030448(CHEMBL269732 | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN ...)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to FKBP12 (unknown origin) by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetStreptavidin(Streptomyces avidinii)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)
Affinity DataKd:  11nMAssay Description:Binding affinity to Streptomyces avidinii streptavidin by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetStreptavidin(Streptomyces avidinii)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM12(cid_171548 | cid_253 | 5-[(3aS,4S,6aR)-2-oxo-hexah...)
Affinity DataKd:  0nMAssay Description:Binding affinity to Streptomyces avidinii streptavidin by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCalmodulin(Bovine)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50045365(CHEMBL3337496)
Affinity DataKd:  1nMAssay Description:Binding affinity to calmodulin (unknown origin) by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetThiopurine S-methyltransferase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to thiopurine methyltransferase (unknown origin) by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataKi:  0.00600nMAssay Description:Binding affinity to DHFR (unknown origin) by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)