Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50045113
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataIC50: 52nMAssay Description:Inhibition of human 5-HT2B receptor expressed in HEK293-EBNA cells assessed as [3H]PI metabolism by by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataIC50: 59nMAssay Description:Inhibition of human 5-HT7 receptor expressed in CHO cells assessed as cAMP production by EIA systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045494(CHEMBL3310115)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045493(CHEMBL3310116)
Affinity DataKi:  0.670nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045490(CHEMBL3310714)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045480(CHEMBL3310111)
Affinity DataKi:  0.810nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045486(CHEMBL3310121)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045482(CHEMBL3310112)
Affinity DataKi:  0.910nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045489(CHEMBL3310713)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045478(CHEMBL3310109)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045496(CHEMBL3310113)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045479(CHEMBL3310110)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045477(CHEMBL3139188)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045490(CHEMBL3310714)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045489(CHEMBL3310713)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045487(CHEMBL3310122)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045496(CHEMBL3310113)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045487(CHEMBL3310122)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045491(CHEMBL3310118)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045492(CHEMBL3310117)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045495(CHEMBL3310114)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045480(CHEMBL3310111)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045477(CHEMBL3139188)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045484(CHEMBL3310120)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045482(CHEMBL3310112)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045494(CHEMBL3310115)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045483(CHEMBL3310119)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045478(CHEMBL3310109)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045492(CHEMBL3310117)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045484(CHEMBL3310120)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045491(CHEMBL3310118)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045486(CHEMBL3310121)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045493(CHEMBL3310116)
Affinity DataKi:  87nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045495(CHEMBL3310114)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045483(CHEMBL3310119)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi:  390nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045479(CHEMBL3310110)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed