Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50001589
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016653(CHEMBL19187 | N-Benzyl-4-chloro-2-(2,5-dioxo-imida...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016646(CHEMBL19427 | 5-[5-Chloro-2-(pentane-1-sulfonyl)-p...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016634(CHEMBL277520 | 5-(5-Chloro-2-methanesulfonyl-pheny...)
Affinity DataIC50: 50nMAssay Description:Compound was evaluated for inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016629(CHEMBL19711 | 4-Chloro-2-(2,5-dioxo-imidazolidin-4...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016640(CHEMBL19744 | 4-Chloro-2-(2,5-dioxo-imidazolidin-4...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016642(CHEMBL279878 | 4-Chloro-2-(2,5-dioxo-imidazolidin-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016644(CHEMBL19495 | 5-(5-Chloro-2-ethanesulfonyl-phenyl)...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016633(CHEMBL19532 | 4-Chloro-2-(2,5-dioxo-imidazolidin-4...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016652(CHEMBL19316 | 5-{5-Chloro-2-[2-(4-chloro-phenyl)-e...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016630(CHEMBL18854 | 5-[5-Chloro-2-(hexane-1-sulfonyl)-ph...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016632(CHEMBL274727 | 4-Chloro-2-(2,5-dioxo-imidazolidin-...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016638(CHEMBL443492 | 5-[5-Chloro-2-(propane-1-sulfonyl)-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016631(CHEMBL279274 | 5-(5-Chloro-2-methanesulfinyl-pheny...)
Affinity DataIC50: 250nMAssay Description:Compound was evaluated for inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016637(CHEMBL19502 | 5-(5-Chloro-2-methanesulfonyl-3-meth...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016645(CHEMBL19649 | 5-[5-Chloro-2-(4-chloro-phenylmethan...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016655(CHEMBL18865 | 5-[5-Chloro-2-(propane-2-sulfonyl)-p...)
Affinity DataIC50: 380nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016635(CHEMBL19781 | 5-[5-Chloro-2-(4-chloro-phenylmethan...)
Affinity DataIC50: 470nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against human placental aldose reductase (HPAR) with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016647(CHEMBL429059 | 4-Chloro-2-(2,5-dioxo-imidazolidin-...)
Affinity DataIC50: 580nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016641(CHEMBL440790 | 5-(5-Chloro-2-methanesulfonyl-3-tri...)
Affinity DataIC50: 580nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016628(CHEMBL19885 | 5-(5-Fluoro-2-methanesulfonyl-phenyl...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016656(CHEMBL277427 | 5-(3,5-Dichloro-2-methanesulfonyl-p...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016649(CHEMBL278584 | 5-(5-Chloro-2-methylsulfanyl-phenyl...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016654(CHEMBL19064 | N-Butyl-4-chloro-2-(2,5-dioxo-imidaz...)
Affinity DataIC50: 700nMAssay Description:Compound was evaluated for inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016648(CHEMBL19789 | 5-[5-Chloro-2-(4-chloro-benzylsulfan...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016650(CHEMBL275868 | 4-Chloro-2-(2,5-dioxo-imidazolidin-...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016639(CHEMBL278565 | 5-(5-Chloro-2-methoxy-phenyl)-imida...)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016636(CHEMBL280357 | 4-Chloro-2-(2,5-dioxo-imidazolidin-...)
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016651(CHEMBL19392 | 4-Chloro-2-(2,5-dioxo-imidazolidin-4...)
Affinity DataIC50: 5.63E+3nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016643(CHEMBL19746 | 5-(5-Fluoro-2-methoxy-phenyl)-imidaz...)
Affinity DataIC50: 7.47E+3nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed