Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50006204
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497782(CHEMBL3330130)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497795(CHEMBL3330129)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497793(CHEMBL3330125)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497783(CHEMBL3330124)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497799(CHEMBL3330122)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50069365(CHEMBL3330104 | US9670191, F25)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497796(CHEMBL3330127)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497792(CHEMBL3330121)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497794(CHEMBL3330126)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497790(CHEMBL3330105)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497791(CHEMBL3330118)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497788(CHEMBL3330108)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497777(CHEMBL3330114)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497800(CHEMBL3330128)
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497781(CHEMBL3329229)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497797(CHEMBL3330120)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497780(CHEMBL3330115)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497789(CHEMBL3330107)
Affinity DataIC50: 109nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497787(CHEMBL3330109)
Affinity DataIC50: 114nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497778(CHEMBL3330131)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497805(CHEMBL3330112)
Affinity DataIC50: 154nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497804(CHEMBL3330103)
Affinity DataIC50: 187nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497795(CHEMBL3330129)
Affinity DataIC50: 210nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497785(CHEMBL3330113)
Affinity DataIC50: 247nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497792(CHEMBL3330121)
Affinity DataIC50: 250nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497802(CHEMBL3330110)
Affinity DataIC50: 268nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497779(CHEMBL3330123)
Affinity DataIC50: 308nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497782(CHEMBL3330130)
Affinity DataIC50: 320nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497786(CHEMBL3330111)
Affinity DataIC50: 384nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497801(CHEMBL3330119)
Affinity DataIC50: 394nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50069365(CHEMBL3330104 | US9670191, F25)
Affinity DataIC50: 430nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497790(CHEMBL3330105)
Affinity DataIC50: 480nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497793(CHEMBL3330125)
Affinity DataIC50: 480nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM187525(US9670191, F19)
Affinity DataIC50: 615nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM187526(US9670191, F20)
Affinity DataIC50: 617nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM187247(US9670191, F2)
Affinity DataIC50: 695nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497799(CHEMBL3330122)
Affinity DataIC50: 700nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497783(CHEMBL3330124)
Affinity DataIC50: 760nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497791(CHEMBL3330118)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497794(CHEMBL3330126)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497798(CHEMBL3330117)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497784(CHEMBL3330116)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497788(CHEMBL3330108)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497777(CHEMBL3330114)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497803(CHEMBL3330106)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497796(CHEMBL3330127)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50329427(5-(2-Amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-c...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed