Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 11
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65470(Quinolone-based HDAC inhibitor 4i)
Affinity DataIC50: 0.100nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65471(Quinolone-based HDAC inhibitor 4j)
Affinity DataIC50: 1.5nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65478(Quinolone-based HDAC inhibitor 4o)
Affinity DataIC50: 10nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65481(Quinolone-based HDAC inhibitor 4r)
Affinity DataIC50: 28nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65479(Quinolone-based HDAC inhibitor 4p)
Affinity DataIC50: 28nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65458(Quinolone-based HDAC inhibitor 4a)
Affinity DataIC50: 32nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65475(Quinolone-based HDAC inhibitor 4l)
Affinity DataIC50: 32nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65474(Quinolone-based HDAC inhibitor 4k)
Affinity DataIC50: 32nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65485(Quinolone-based HDAC inhibitor 4v)
Affinity DataIC50: 39nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65463(Quinolone-based HDAC inhibitor 4c)
Affinity DataIC50: 39nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65480(Quinolone-based HDAC inhibitor 4q)
Affinity DataIC50: 40nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65469(Quinolone-based HDAC inhibitor 4h)
Affinity DataIC50: 42nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65476(Quinolone-based HDAC inhibitor 4m)
Affinity DataIC50: 75nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65484(Quinolone-based HDAC inhibitor 4u)
Affinity DataIC50: 85nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65468(Quinolone-based HDAC inhibitor 4g)
Affinity DataIC50: 90nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65472(Quinolone-based HDAC inhibitor 4w)
Affinity DataIC50: 95nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 110nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65464(Quinolone-based HDAC inhibitor 4d)
Affinity DataIC50: 120nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65477(Quinolone-based HDAC inhibitor 4n)
Affinity DataIC50: 150nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65483(Quinolone-based HDAC inhibitor 4t)
Affinity DataIC50: 230nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65459(Quinolone-based HDAC inhibitor 4b)
Affinity DataIC50: 270nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65482(Quinolone-based HDAC inhibitor 4s)
Affinity DataIC50: 330nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65467(Quinolone-based HDAC inhibitor 4f)
Affinity DataIC50: 390nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandPNGBDBM65466(Quinolone-based HDAC inhibitor 4e)
Affinity DataIC50: 410nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed