Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50045232
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataKd:  3.60E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataKd:  1.83E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051116(CHEMBL3318284)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of SETD8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051121(CHEMBL3318289)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051122(CHEMBL3318290)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of methyltransferase activity of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli assessed as decrease in methylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051133(CHEMBL3318301)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051123(CHEMBL3318291)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051127(CHEMBL3318295)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051126(CHEMBL3318294)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051125(CHEMBL3318293)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051128(CHEMBL3318296)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051124(CHEMBL3318292)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051119(CHEMBL3318287)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051386(CHEMBL3318305)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051384(CHEMBL3318304)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 3.77E+4nMAssay Description:Displacement of FITC-labeled H4K20me (1-24) from SETD8 (unknown origin) catalytic domain expressed in Escherichia coli by fluorescence polarization a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051120(CHEMBL3318288)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051129(CHEMBL3318297)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051118(CHEMBL3318286)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051131(CHEMBL3318299)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DOT1L (unknown origin) by filter-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase 2A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MLL1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DNMT1 (unknown origin) assessed as using dsDNA substrate by radioactive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SMYD2 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase KMT5C(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SUV420H2 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase KMT5B(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SUV420H1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT3 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SETD7 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SUV39H2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SUV39H2 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GLP (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETDB1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SETDB1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of G9a (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051398(CHEMBL3318308)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051390(CHEMBL3318307)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051387(CHEMBL3318306)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051130(CHEMBL3318298)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051239(CHEMBL3318303)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051134(CHEMBL3318302)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50051132(CHEMBL3318300)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed