Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 6238
TargetFatty acid synthase(Human)
Glaxosmithkline

LigandPNGBDBM119133((S)-4-(4-(Benzofuran-5-yl)phenyl)-3-((1-(cycloprop...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of FAS by GSK2194069 was measured by an endpoint assay for thiols using a fluorescent maleimide.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Glaxosmithkline

LigandPNGBDBM119132(2-([1,1'-Biphenyl]-4-yl)-1-((1-(cyclopropaneca...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FAS by benzimidazole was measured by an endpoint assay for NADPH consumption.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMed