Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50044784
TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330795(2-hydroxy-5-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50: 70nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50157547(7,8,3',4'-tetrahydroxyflavone | 2-(3,4-dihydroxyph...)
Affinity DataIC50: 70nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330794(2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone | ...)
Affinity DataIC50: 90nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetTyrosinase(Human)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330795(2-hydroxy-5-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50: 1.15E+3nMAssay Description:Competitive inhibition of tyrosinase in human G-361 cells incubated for 10 mins measured for 2 hrs by MBTH-based spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50192743(CHEBI:50205 | 3,4-Dihydroxybenzaldehyde | Protocat...)
Affinity DataIC50: 2.89E+3nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50192745(CHEMBL3343985 | CHEBI:75844)
Affinity DataIC50: 8.40E+3nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetTyrosinase(Human)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330794(2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone | ...)
Affinity DataIC50: 8.98E+3nMAssay Description:Competitive inhibition of tyrosinase in human G-361 cells incubated for 10 mins measured for 2 hrs by MBTH-based spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetTyrosinase(Human)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50192746(CHEMBL3343986)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of tyrosinase in human HMV-2 melanoma cells after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50: 9.53E+3nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50192744(TRIOLEIN)
Affinity DataIC50: 3.00E+4nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 5.37E+4nMAssay Description:Non-competitive inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetTyrosinase(Human)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 5.71E+5nMAssay Description:Competitive inhibition of tyrosinase in human G-361 cells incubated for 10 mins measured for 2 hrs by MBTH-based spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetTyrosinase(Human)
Institute For Theoretical Medicine

Curated by ChEMBL
LigandPNGBDBM50330793(2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Competitive inhibition of tyrosinase in human G-361 cells incubated for 10 mins measured for 2 hrs by MBTH-based spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed