Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50006187
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM59087(CHEMBL258765 | Fascaplysin | Fasca-plysi)
Affinity DataIC50: 410nMAssay Description:Binding affinity to human CDK4/cyclinD1 using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188071(biphenyl-4-carboxylic acid [2-(1H-indol-3-yl)-ethy...)
Affinity DataIC50: 6.20E+3nMAssay Description:Binding affinity to human CDK4/cyclinD1 using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(N-(2-(1H-indol-3-yl)ethyl)-4-chloro-N-methylbenzam...)
Affinity DataIC50: 3.80E+4nMAssay Description:Binding affinity to human CDK4/cyclinD1 using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188064(N-(2-(1H-indol-3-yl)ethyl)-4-tert-butyl-N-methylbe...)
Affinity DataIC50: 4.90E+4nMAssay Description:Binding affinity to human CDK4/cyclinD1 using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM59087(CHEMBL258765 | Fascaplysin | Fasca-plysi)
Affinity DataIC50: 2.50E+5nMAssay Description:Binding affinity to human CDK1/cyclinB1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM59087(CHEMBL258765 | Fascaplysin | Fasca-plysi)
Affinity DataIC50: 2.50E+5nMAssay Description:Binding affinity to human CDK2/cyclinA using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM59087(CHEMBL258765 | Fascaplysin | Fasca-plysi)
Affinity DataIC50: 2.50E+5nMAssay Description:Binding affinity to human CDK2/cyclinEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM59087(CHEMBL258765 | Fascaplysin | Fasca-plysi)
Affinity DataIC50: 2.50E+5nMAssay Description:Binding affinity to human CDK9/cyclinT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188071(biphenyl-4-carboxylic acid [2-(1H-indol-3-yl)-ethy...)
Affinity DataIC50: 5.00E+5nMAssay Description:Binding affinity to human CDK1/cyclinB1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(N-(2-(1H-indol-3-yl)ethyl)-4-chloro-N-methylbenzam...)
Affinity DataIC50: 5.00E+5nMAssay Description:Binding affinity to human CDK1/cyclinB1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188064(N-(2-(1H-indol-3-yl)ethyl)-4-tert-butyl-N-methylbe...)
Affinity DataIC50: 5.00E+5nMAssay Description:Binding affinity to human CDK1/cyclinB1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188071(biphenyl-4-carboxylic acid [2-(1H-indol-3-yl)-ethy...)
Affinity DataIC50: 5.21E+5nMAssay Description:Binding affinity to human CDK2/cyclinA using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188064(N-(2-(1H-indol-3-yl)ethyl)-4-tert-butyl-N-methylbe...)
Affinity DataIC50: 6.58E+5nMAssay Description:Binding affinity to human CDK2/cyclinA using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(N-(2-(1H-indol-3-yl)ethyl)-4-chloro-N-methylbenzam...)
Affinity DataIC50: 7.31E+5nMAssay Description:Binding affinity to human CDK2/cyclinA using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(N-(2-(1H-indol-3-yl)ethyl)-4-chloro-N-methylbenzam...)
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity to human CDK9/cyclinT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188064(N-(2-(1H-indol-3-yl)ethyl)-4-tert-butyl-N-methylbe...)
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity to human CDK9/cyclinT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188071(biphenyl-4-carboxylic acid [2-(1H-indol-3-yl)-ethy...)
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity to human CDK9/cyclinT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed