Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50044841
LigandPNGBDBM50032547(CHEMBL3354181)
Affinity DataIC50: 1nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032540(CHEMBL3354179)
Affinity DataIC50: 2nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032543(CHEMBL3354180)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032600(CHEMBL3354171)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032529(CHEMBL3354178)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032471(CHEMBL3354177)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032607(CHEMBL3354175)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032602(CHEMBL3354173)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032550(CHEMBL3354182)
Affinity DataIC50: 12nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032601(CHEMBL3354172)
Affinity DataIC50: 19nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032590(CHEMBL3354168)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032605(CHEMBL3354174)
Affinity DataIC50: 39nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032588(CHEMBL3354167)
Affinity DataIC50: 42nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032592(CHEMBL3354169)
Affinity DataIC50: 45nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50032593(CHEMBL3354170)
Affinity DataIC50: 67nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032587(CHEMBL3354166)
Affinity DataIC50: 98nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032569(CHEMBL3354160)
Affinity DataIC50: 150nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032609(CHEMBL3354155)
Affinity DataIC50: 160nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032554(CHEMBL3354157)
Affinity DataIC50: 310nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032608(CHEMBL3354176)
Affinity DataIC50: 380nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032540(CHEMBL3354179)
Affinity DataIC50: 380nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032471(CHEMBL3354177)
Affinity DataIC50: 480nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032547(CHEMBL3354181)
Affinity DataIC50: 520nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032543(CHEMBL3354180)
Affinity DataIC50: 640nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032607(CHEMBL3354175)
Affinity DataIC50: 720nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032573(CHEMBL3354161)
Affinity DataIC50: 740nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032601(CHEMBL3354172)
Affinity DataIC50: 820nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032578(CHEMBL3354164)
Affinity DataIC50: 920nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032529(CHEMBL3354178)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032578(CHEMBL3354164)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032602(CHEMBL3354173)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032552(CHEMBL3354156)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032600(CHEMBL3354171)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032585(CHEMBL3354165)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032592(CHEMBL3354169)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032593(CHEMBL3354170)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032550(CHEMBL3354182)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032605(CHEMBL3354174)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032577(CHEMBL3354163)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032590(CHEMBL3354168)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032608(CHEMBL3354176)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032587(CHEMBL3354166)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032569(CHEMBL3354160)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032559(CHEMBL3354159)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL
LigandPNGBDBM50032588(CHEMBL3354167)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032577(CHEMBL3354163)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032557(CHEMBL3354158)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032574(CHEMBL3354162)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed