Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50045380
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059637(GSK-2636771 | GSK2636771 | US10660898, Example 31)
Affinity DataIC50: 0.890nMAssay Description:Inhibition of PI3K p110beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059642(CHEMBL3393593)
Affinity DataIC50: 2nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM25018(thienopyrimidine derivative, 1 | CHEMBL541643 | 3-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50308767(PKI-402 | 1-[4-(3-Ethyl-7-morpholin-4-yl-3H-[1,2,3...)
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50308767(PKI-402 | 1-[4-(3-Ethyl-7-morpholin-4-yl-3H-[1,2,3...)
Affinity DataIC50: 3nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50392138(CHEMBL2152768)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PI3K p110delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50358208(CHEMBL1921986)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059639(CHEMBL3393500)
Affinity DataIC50: 5nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3K p110gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059639(CHEMBL3393500)
Affinity DataIC50: 5nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059640(CHEMBL2140173)
Affinity DataIC50: 6nMAssay Description:Inhibition of ATM kinase in human glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50358208(CHEMBL1921986)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of PI3K p110gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50308767(PKI-402 | 1-[4-(3-Ethyl-7-morpholin-4-yl-3H-[1,2,3...)
Affinity DataIC50: 7nMAssay Description:Inhibition of PI3K p110beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059638(CHEMBL3393499)
Affinity DataIC50: 13nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50156495(NU-7441 | NU-7432 | 8-Dibenzothiophen-4-yl-2-morph...)
Affinity DataIC50: 14nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50308767(PKI-402 | 1-[4-(3-Ethyl-7-morpholin-4-yl-3H-[1,2,3...)
Affinity DataIC50: 14nMAssay Description:Inhibition of PI3K p110delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50358208(CHEMBL1921986)
Affinity DataIC50: 14nMAssay Description:Inhibition of PI3K p110delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059635(CHEMBL3393066)
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50308767(PKI-402 | 1-[4-(3-Ethyl-7-morpholin-4-yl-3H-[1,2,3...)
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3K p110gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50358208(CHEMBL1921986)
Affinity DataIC50: 17nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059648(CHEMBL3393594)
Affinity DataIC50: 23nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059635(CHEMBL3393066)
Affinity DataIC50: 25nMAssay Description:Inhibition of PI3K p110gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50358208(CHEMBL1921986)
Affinity DataIC50: 27nMAssay Description:Inhibition of PI3K p110beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50017675(CHEMBL3288951)
Affinity DataIC50: 34nMAssay Description:Inhibition of DNA-PK purified from HeLa nuclear extracts assessed as EPPLSQEAFADLWKKR peptide substrate phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059641(CHEMBL3393501)
Affinity DataIC50: 35nMAssay Description:Inhibition of DNA-PK purified from HeLa nuclear extracts assessed as EPPLSQEAFADLWKKR peptide substrate phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059635(CHEMBL3393066)
Affinity DataIC50: 37nMAssay Description:Inhibition of PI3K p110delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50156503(8-Dibenzofuran-4-yl-2-morpholin-4-yl-chromen-4-one...)
Affinity DataIC50: 41nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 44nMAssay Description:Inhibition of PI3K p110beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 49nMAssay Description:Inhibition of PI3K p110delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059635(CHEMBL3393066)
Affinity DataIC50: 68nMAssay Description:Inhibition of PI3K p110beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50398036(CHEMBL1317546)
Affinity DataIC50: 120nMAssay Description:Inhibition of DNA-PK purified from HeLa nuclear extracts assessed as EPPLSQEAFADLWKKR peptide substrate phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50132355(2-(4-Chloro-phenyl)-6-morpholin-4-yl-pyran-4-one |...)
Affinity DataIC50: 180nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50132361(2-(4-methoxyphenyl)-6-morpholino-4H-pyran-4-one | ...)
Affinity DataIC50: 220nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50098126(LY-293646 | 2-morpholino-4H-benzo[h]chromen-4-one ...)
Affinity DataIC50: 230nMAssay Description:Inhibition of DNA-PK purified from human HeLa nuclear extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50132365(6-(4-methoxyphenyl)-2-morpholin-4-yl-4H-thiopyran-...)
Affinity DataIC50: 280nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50398037(CHEMBL2181110)
Affinity DataIC50: 400nMAssay Description:Inhibition of DNA-PK purified from HeLa nuclear extracts assessed as EPPLSQEAFADLWKKR peptide substrate phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50132369(6-(4-chlorophenyl)-2-morpholin-4-yl-4H-thiopyran-4...)
Affinity DataIC50: 530nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 550nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50319915(4-morpholino-7-(thiophen-2-yl)-2H-chromen-2-one | ...)
Affinity DataIC50: 600nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50447094(CHEMBL1972466)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50159679(6-Methoxy-4-morpholin-4-yl-chromen-2-one | 6-metho...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of DNA-PK purified from human HeLa nuclear extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059597(CHEMBL3393502)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PI3K p110delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50447094(CHEMBL1972466)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PI3K p110beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Rat)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of rat derived mTOR using [gamma32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50270042((2-hydroxy-4-morpholinophenyl)(phenyl)methanone | ...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of PI3K p110beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50059636(CHEMBL3218573)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PI3K p110beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
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