Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50001643
TargetAldo-keto reductase family 1 member B1 [K65Q](Bovine)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of bovine lens aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1 [K65Q](Bovine)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50016901(CHEMBL348759 | (2-Methyl-3-oxo-3H-phenalen-1-yl)-a...)
Affinity DataIC50: 270nMAssay Description:In vitro inhibition of bovine lens aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 540nMAssay Description:Inhibition of aldose reductase (or polyol accumulation) in isolated rat sciatic nerve by compound at 10e-5 M concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1 [K65Q](Bovine)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50016902(CHEMBL168106 | [Methyl-(naphthalene-1-carbothioyl)...)
Affinity DataIC50: 730nMAssay Description:In vitro inhibition of bovine lens aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50016901(CHEMBL348759 | (2-Methyl-3-oxo-3H-phenalen-1-yl)-a...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of aldose reductase (or polyol accumulation) in isolated rat sciatic nerve by compound at 10e-5 M concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed