Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50045686
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA (cytosine-5)-methyltransferase 3B(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075103(CHEBI:48202 | Nanafrocin)
Affinity DataIC50: 500nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3b expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 500nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM24774(2,3-dichloro-1,4-dihydronaphthalene-1,4-dione | CH...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50448484(CHEMBL3126646)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3a expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075193(CHEMBL3414630)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50430056(CHEMBL2336409 | SGI-1027)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50430056(CHEMBL2336409 | SGI-1027)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3b expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50430056(CHEMBL2336409 | SGI-1027)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3a expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50448484(CHEMBL3126646)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075182(CHEMBL3414633)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075185(CHEMBL3414632)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075192(CHEMBL3414631)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075182(CHEMBL3414633)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3a expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075185(CHEMBL3414632)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His6-tagged human recombinant DNMT3a expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50357280(CHEMBL1916517)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50075194(CHEMBL403716)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50389497(CHEMBL1564869)
Affinity DataIC50: 3.90E+5nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Cnrs-Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM39344(PROCAINAMIDE | PROCAINAMIDE HYDROCHLORIDE | 4-azan...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed