Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50001658
TargetThymidylate synthase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50008294(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 10nMAssay Description:Inhibition of pure human thymidylate synthase from extract of Manca human lymphoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50008294(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 21nMAssay Description:Inhibition of thymidylate synthase in Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50012244(CHEMBL25889 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-qu...)
Affinity DataIC50: 60nMAssay Description:Inhibition of pure human thymidylate synthase from extract of Manca human lymphoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50012244(CHEMBL25889 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-qu...)
Affinity DataIC50: 60nMAssay Description:Inhibition of pure human thymidylate synthase from extract of Manca human lymphoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50012244(CHEMBL25889 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-qu...)
Affinity DataIC50: 100nMAssay Description:Inhibition of thymidylate synthase in Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50008294(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of dihydrofolate reductase in Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50017081(CHEMBL24599 | 2-{4-[(4-Oxo-2-trifluoromethyl-3,4-d...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of purified human thymidylate synthase from a SV40-transformed human fibroblast cell line cloned in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50017080(CHEMBL24701 | 2-{4-[(2,3-Dimethyl-4-oxo-3,4-dihydr...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of purified human thymidylate synthase from a SV40-transformed human fibroblast cell line cloned in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50012244(CHEMBL25889 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-qu...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of GAR formyltransferase in Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50012244(CHEMBL25889 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-qu...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of GAR formyltransferase from extract of Manca human lymphoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50012244(CHEMBL25889 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-qu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of pure human dihydrofolate reductase (DHFR) from lymphoblastoid cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50012244(CHEMBL25889 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-qu...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of dihydrofolate reductase in Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50012244(CHEMBL25889 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-qu...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of AICAR formyltransferase in Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50012244(CHEMBL25889 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-qu...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of AICAR formyltransferase from extract of Manca human lymphoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed