Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 5697
TargetBeta-adrenergic receptor kinase 1(Human)
Merck Sharp and Dohme Research Laboratories

LigandPNGBDBM25392(Isoproterenol,(+) | CHEMBL434 | 4-[1-hydroxy-2-(pr...)
Affinity DataKd:  200nMAssay Description:The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetBeta-adrenergic receptor kinase 1(Human)
Merck Sharp and Dohme Research Laboratories

LigandPNGBDBM84342(EPINEPHRINE | 4-[1-hydroxy-2-(methylamino)ethyl]be...)
Affinity DataKd:  610nMAssay Description:The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetBeta-adrenergic receptor kinase 1(Human)
Merck Sharp and Dohme Research Laboratories

LigandPNGBDBM92678(2-(tert-butylamino)-1-phenylethan-1-ol, 4)
Affinity DataKd:  4.10E+3nMAssay Description:The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetBeta-adrenergic receptor kinase 1(Human)
Merck Sharp and Dohme Research Laboratories

LigandPNGBDBM92680(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenol, 8)
Affinity DataKd:  5.20E+3nMAssay Description:The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetBeta-adrenergic receptor kinase 1(Human)
Merck Sharp and Dohme Research Laboratories

LigandPNGBDBM25770(Terbutaline,(+/-) | Brethine | 5-[2-(tert-butylami...)
Affinity DataKd:  7.40E+3nMAssay Description:The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetBeta-adrenergic receptor kinase 1(Human)
Merck Sharp and Dohme Research Laboratories

LigandPNGBDBM50295572(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)
Affinity DataKd:  1.30E+4nMAssay Description:The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetBeta-adrenergic receptor kinase 1(Human)
Merck Sharp and Dohme Research Laboratories

LigandPNGBDBM92679(3-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenol, 7)
Affinity DataKd:  3.00E+4nMAssay Description:The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetBeta-adrenergic receptor kinase 1(Human)
Merck Sharp and Dohme Research Laboratories

LigandPNGBDBM46041(1-(3,4-dihydroxyphenyl)-2-[(propan-2-yl)amino]etha...)
Affinity DataKd:  9.00E+5nMAssay Description:The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed