Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 50045599
TargetCytochrome P450 3A4(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070060(CHEMBL3407822)
Affinity DataIC50: 300nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-(trifluoromethyl)coumarin as substrate assessed as formation of 7-hydroxy-4-trifluoromethylcoumarin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070061(CHEMBL3407821)
Affinity DataIC50: 900nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-(trifluoromethyl)coumarin as substrate assessed as formation of 7-hydroxy-4-trifluoromethylcoumarin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070042(CHEMBL3407810)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-(trifluoromethyl)coumarin as substrate assessed as formation of 7-hydroxy-4-trifluoromethylcoumarin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070038(CHEMBL3407814)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-(trifluoromethyl)coumarin as substrate assessed as formation of 7-hydroxy-4-trifluoromethylcoumarin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070060(CHEMBL3407822)
Affinity DataKi:  18nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070042(CHEMBL3407810)
Affinity DataKi:  19nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070041(CHEMBL3407811)
Affinity DataKi:  32nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070039(CHEMBL3407813)
Affinity DataKi:  40nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070038(CHEMBL3407814)
Affinity DataKi:  54nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070040(CHEMBL3407812)
Affinity DataKi:  56nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070061(CHEMBL3407821)
Affinity DataKi:  60nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255365(CHEMBL1277870 | (+/-)-cis-N1-((3S,4S)-4-((6-amino-...)
Affinity DataKi:  70nMAssay Description:Binding affinity to recombinant human neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070038(CHEMBL3407814)
Affinity DataKi:  125nMAssay Description:Binding affinity to recombinant human neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070041(CHEMBL3407811)
Affinity DataKi:  125nMAssay Description:Binding affinity to recombinant human neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070060(CHEMBL3407822)
Affinity DataKi:  137nMAssay Description:Binding affinity to recombinant human neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070037(CHEMBL3407815)
Affinity DataKi:  138nMAssay Description:Binding affinity to recombinant human neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070043(CHEMBL3407809)
Affinity DataKi:  138nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070059(CHEMBL3407823)
Affinity DataKi:  150nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070037(CHEMBL3407815)
Affinity DataKi:  183nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070042(CHEMBL3407810)
Affinity DataKi:  193nMAssay Description:Binding affinity to recombinant human neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070042(CHEMBL3407810)
Affinity DataKi:  200nMAssay Description:Binding affinity to human adrenergic alpha-2C receptor after 90 mins by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070042(CHEMBL3407810)
Affinity DataKi:  200nMAssay Description:Binding affinity to human sigma-1 receptor after 90 mins by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070061(CHEMBL3407821)
Affinity DataKi:  303nMAssay Description:Binding affinity to recombinant human neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070039(CHEMBL3407813)
Affinity DataKi:  358nMAssay Description:Binding affinity to recombinant human neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070040(CHEMBL3407812)
Affinity DataKi:  359nMAssay Description:Binding affinity to recombinant human neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070058(CHEMBL3407806)
Affinity DataKi:  368nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070042(CHEMBL3407810)
Affinity DataKi:  500nMAssay Description:Binding affinity to human dopamine D3 receptor after 90 mins by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070042(CHEMBL3407810)
Affinity DataKi:  500nMAssay Description:Binding affinity to human 5-HT2A receptor after 90 mins by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070042(CHEMBL3407810)
Affinity DataKi:  500nMAssay Description:Binding affinity to human 5-HT1A receptor after 90 mins by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070043(CHEMBL3407809)
Affinity DataKi:  758nMAssay Description:Binding affinity to recombinant human neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070042(CHEMBL3407810)
Affinity DataKi:  770nMAssay Description:Binding affinity to recombinant mouse macrophage inducible NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-argini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070059(CHEMBL3407823)
Affinity DataKi:  873nMAssay Description:Binding affinity to recombinant human neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070041(CHEMBL3407811)
Affinity DataKi:  910nMAssay Description:Binding affinity to recombinant mouse macrophage inducible NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-argini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070043(CHEMBL3407809)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to recombinant mouse macrophage inducible NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-argini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070038(CHEMBL3407814)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity to recombinant mouse macrophage inducible NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-argini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070040(CHEMBL3407812)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity to recombinant mouse macrophage inducible NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-argini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070060(CHEMBL3407822)
Affinity DataKi:  2.14E+3nMAssay Description:Binding affinity to recombinant mouse macrophage inducible NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-argini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070057(CHEMBL3407808)
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070039(CHEMBL3407813)
Affinity DataKi:  2.90E+3nMAssay Description:Binding affinity to recombinant mouse macrophage inducible NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-argini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070059(CHEMBL3407823)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity to recombinant mouse macrophage inducible NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-argini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070037(CHEMBL3407815)
Affinity DataKi:  3.40E+3nMAssay Description:Binding affinity to recombinant mouse macrophage inducible NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-argini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070040(CHEMBL3407812)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity to recombinant bovine endothelial NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070043(CHEMBL3407809)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity to recombinant bovine endothelial NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070068(CHEMBL3407805 | US9878996, Compound 2)
Affinity DataKi:  4.70E+3nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070042(CHEMBL3407810)
Affinity DataKi:  4.95E+3nMAssay Description:Binding affinity to recombinant bovine endothelial NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070066(CHEMBL3407816)
Affinity DataKi:  5.50E+3nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070058(CHEMBL3407806)
Affinity DataKi:  6.40E+3nMAssay Description:Binding affinity to recombinant mouse macrophage inducible NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-argini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070041(CHEMBL3407811)
Affinity DataKi:  8.10E+3nMAssay Description:Binding affinity to recombinant bovine endothelial NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070067(CHEMBL3407807)
Affinity DataKi:  8.70E+3nMAssay Description:Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50070060(CHEMBL3407822)
Affinity DataKi:  1.03E+4nMAssay Description:Binding affinity to recombinant bovine endothelial NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2016
Entry Details Article
PubMed
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