Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50045010
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041529(CHEMBL3358391)
Affinity DataIC50: 600nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041522(CHEMBL3358386)
Affinity DataIC50: 900nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50000029(suramin | SURAMIN HEXASODIUM | CHEMBL265502 | 4-Me...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant SIRT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041514(CHEMBL3358382)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant SIRT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041530(CHEMBL3358375)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041519(CHEMBL3358384)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041523(CHEMBL3358387)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041531(CHEMBL3358377)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM27507(pyridine-3-carboxamide | nicotinamide | 3-Pyridine...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant SIRT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041528(CHEMBL3358390)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041521(CHEMBL3358385)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041515(CHEMBL3358383)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant SIRT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041478(CHEMBL3358381)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041526(CHEMBL3358388)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human SIRT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human SIRT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human SIRT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human SIRT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041527(CHEMBL3358389)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041529(CHEMBL3358391)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant SIRT1 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 45 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50041529(CHEMBL3358391)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant SIRT3 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 45 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed