Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50045652
TargetUbiquitin carboxyl-terminal hydrolase isozyme L5(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50072959(CHEMBL3410535)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of GST-tagged UCHL5 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins before substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetUbl carboxyl-terminal hydrolase 18(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50072960(CHEMBL3410537)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of recombinant human USP18 (16 to 372 aa) expressed in Sf9 cells using ISG15-AMC as substrate preincubated for 30 mins before substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50072959(CHEMBL3410535)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of USP2 catalytic domain (unknown origin) expressed in bacteria using Ub-AMC as substrate preincubated for 30 mins before substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetUbl carboxyl-terminal hydrolase 18(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50072959(CHEMBL3410535)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of recombinant human USP18 (16 to 372 aa) expressed in Sf9 cells using ISG15-AMC as substrate preincubated for 30 mins before substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L5(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50072960(CHEMBL3410537)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of GST-tagged UCHL5 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins before substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed