Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50045719
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078322(CHEMBL3414710)
Affinity DataIC50: 24nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078321(CHEMBL3414711 | US9260455, 7)
Affinity DataIC50: 25nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078324(CHEMBL3414708 | US9260455, 8)
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078349(CHEMBL3414707 | US9260455, 3)
Affinity DataIC50: 39nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078320(CHEMBL3414700 | US9260455, 4)
Affinity DataIC50: 59nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078323(CHEMBL3414709)
Affinity DataIC50: 59nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM142394(US8933221, 4)
Affinity DataIC50: 61nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078321(CHEMBL3414711 | US9260455, 7)
Affinity DataIC50: 150nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM142369(US8933221, 10)
Affinity DataIC50: 265nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078322(CHEMBL3414710)
Affinity DataIC50: 280nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078352(CHEMBL3414705)
Affinity DataIC50: 375nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078323(CHEMBL3414709)
Affinity DataIC50: 470nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078320(CHEMBL3414700 | US9260455, 4)
Affinity DataIC50: 670nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078349(CHEMBL3414707 | US9260455, 3)
Affinity DataIC50: 700nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078324(CHEMBL3414708 | US9260455, 8)
Affinity DataIC50: 850nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078351(CHEMBL3414703)
Affinity DataIC50: 850nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM142394(US8933221, 4)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 2D6(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078322(CHEMBL3414710)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078350(CHEMBL3414704)
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing APP695 assessed as sAPPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM142369(US8933221, 10)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078352(CHEMBL3414705)
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078351(CHEMBL3414703)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078321(CHEMBL3414711 | US9260455, 7)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of CatD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078353(CHEMBL3414702)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCathepsin D(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078322(CHEMBL3414710)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of CatD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078323(CHEMBL3414709)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of CatD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078349(CHEMBL3414707 | US9260455, 3)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of CatD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM142394(US8933221, 4)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of CatD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078320(CHEMBL3414700 | US9260455, 4)
Affinity DataIC50: 8.31E+4nMAssay Description:Inhibition of CatD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078350(CHEMBL3414704)
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon Green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078324(CHEMBL3414708 | US9260455, 8)
Affinity DataIC50: 9.14E+4nMAssay Description:Inhibition of CatD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078350(CHEMBL3414704)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CatD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078351(CHEMBL3414703)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CatD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM50078352(CHEMBL3414705)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CatD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Eurofarma Laboratorios

Curated by ChEMBL
LigandPNGBDBM142369(US8933221, 10)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CatD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed