Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50035779
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017536(CHEMBL273786 | Flumezapine | 7-Fluoro-2-methyl-10-...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against dDopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017524(CHEMBL80620 | 7-Chloro-2-ethyl-10-(4-methyl-pipera...)
Affinity DataIC50: 67nMAssay Description:Inhibitory activity against dDopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017536(CHEMBL273786 | Flumezapine | 7-Fluoro-2-methyl-10-...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017521(CHEMBL76550 | 2-Ethyl-7-fluoro-10-(4-methyl-pipera...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against dDopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017527(CHEMBL78278 | 7-Chloro-2-methyl-10-(4-methyl-piper...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against dDopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017530(CHEMBL311973 | 7-Bromo-2-methyl-10-(4-methyl-piper...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017523(CHEMBL308071 | 7-Fluoro-2-methyl-10-(4-methyl-pipe...)
Affinity DataIC50: 840nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017528(CHEMBL76926 | 2-Methyl-10-(4-methyl-piperazin-1-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017534(CHEMBL308387 | 6,7-Dichloro-2-methyl-10-(4-methyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017525(CHEMBL308827 | 7-Fluoro-1,2-dimethyl-10-(4-methyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017523(CHEMBL308071 | 7-Fluoro-2-methyl-10-(4-methyl-pipe...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017522(CHEMBL78980 | 7-Fluoro-1-methyl-10-(4-methyl-piper...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017521(CHEMBL76550 | 2-Ethyl-7-fluoro-10-(4-methyl-pipera...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017526(CHEMBL77058 | 2-Methyl-10-(4-methyl-piperazin-1-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017528(CHEMBL76926 | 2-Methyl-10-(4-methyl-piperazin-1-yl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017526(CHEMBL77058 | 2-Methyl-10-(4-methyl-piperazin-1-yl...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibitory activity against dDopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017534(CHEMBL308387 | 6,7-Dichloro-2-methyl-10-(4-methyl-...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017524(CHEMBL80620 | 7-Chloro-2-ethyl-10-(4-methyl-pipera...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017527(CHEMBL78278 | 7-Chloro-2-methyl-10-(4-methyl-piper...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017530(CHEMBL311973 | 7-Bromo-2-methyl-10-(4-methyl-piper...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017529(CHEMBL77171 | 8,9-Dichloro-5-(4-methyl-piperazin-1...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017535(CHEMBL432937 | 3-Ethyl-7-fluoro-10-(4-methyl-piper...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against dDopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017538(CHEMBL67355 | 5-(4-Methyl-piperazin-1-yl)-11H-benz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017533(CHEMBL307816 | 3-Cyclohexyl-7-fluoro-10-(4-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against dDopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017532(CHEMBL311826 | 3-Methyl-10-(4-methyl-piperazin-1-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017522(CHEMBL78980 | 7-Fluoro-1-methyl-10-(4-methyl-piper...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against dDopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017525(CHEMBL308827 | 7-Fluoro-1,2-dimethyl-10-(4-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against dDopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017535(CHEMBL432937 | 3-Ethyl-7-fluoro-10-(4-methyl-piper...)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017537(CHEMBL76964 | 7-Fluoro-3-methyl-10-(4-methyl-piper...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against dDopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017533(CHEMBL307816 | 3-Cyclohexyl-7-fluoro-10-(4-methyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50017537(CHEMBL76964 | 7-Fluoro-3-methyl-10-(4-methyl-piper...)
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed