Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50045503
TargetG-protein coupled bile acid receptor 1(Human)
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065435(CHEMBL3401351)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065432(CHEMBL3401354)
Affinity DataEC50:  580nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50236238(5beta-cholanic acid-3alpha-ol | CHEMBL1478 | (3alp...)
Affinity DataEC50:  680nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065430(CHEMBL3401356)
Affinity DataEC50:  730nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065433(CHEMBL3401353)
Affinity DataEC50:  750nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065434(CHEMBL3401352)
Affinity DataEC50:  1.05E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065431(CHEMBL3401355)
Affinity DataEC50:  1.49E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM53721(MLS000028461 | Urso 250 | ursodeoxycholicacid | (4...)
Affinity DataEC50:  2.39E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM21676((2S,4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-di...)
Affinity DataEC50:  2.83E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM21674(Chenodeoxycholic Acid | CDCA | (4R)-4-[(1S,2S,5R,7...)
Affinity DataEC50:  6.10E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065429(CHEMBL3401357)
Affinity DataEC50:  9.13E+3nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
The Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50065436(CHEMBL1254261 | 3,7-diketone)
Affinity DataEC50:  1.09E+4nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed