Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50045964
TargetTrypsin(Human)
Rempex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089084(Vaborbactam | CHEMBL3317857)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of trypsin (unknown origin) using N-Bz-R-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetPlasminogen(Human)
Rempex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089084(Vaborbactam | CHEMBL3317857)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of plasmin (unknown origin) using H-D-VLK-pNA as substrate preincubated for 10 mins followed by substrate addition measured for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
Rempex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089084(Vaborbactam | CHEMBL3317857)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of thrombin (unknown origin) using Benz-FVR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Rempex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089084(Vaborbactam | CHEMBL3317857)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of urokinase (unknown origin) using NGK-pNA as substrate preincubated for 10 mins followed by substrate addition measured for 30 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Rempex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089084(Vaborbactam | CHEMBL3317857)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of tissue plasminogen activator (unknown origin) using GK-pNA as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetChymase(Human)
Rempex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089084(Vaborbactam | CHEMBL3317857)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of chymase (unknown origin) using Suc-AAPF-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Rempex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089084(Vaborbactam | CHEMBL3317857)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of dipeptidyl peptidase 7 (unknown origin) using H-Lys-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Rempex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089084(Vaborbactam | CHEMBL3317857)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of neutrophil elastase (unknown origin) using MeOSuc-AAVP-AMC as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetLysosomal protective protein(Human)
Rempex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089084(Vaborbactam | CHEMBL3317857)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of cathepsin A (unknown origin) using MCA-RPPGFSAFK-Dnp as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed