Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 6777
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM152481(Z-L-Am7(betaMe)-QA (3))
Affinity DataIC50: 2nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM152481(Z-L-Am7(betaMe)-QA (3))
Affinity DataIC50: 3.20nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))
Affinity DataIC50: 3.40nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM152481(Z-L-Am7(betaMe)-QA (3))
Affinity DataIC50: 4.90nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))
Affinity DataIC50: 7.5nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))
Affinity DataIC50: 8.20nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM50200895((S)-benzyl 8-(hydroxyamino)-1,8-dioxo-1-(quinolin-...)
Affinity DataIC50: 10nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM50200895((S)-benzyl 8-(hydroxyamino)-1,8-dioxo-1-(quinolin-...)
Affinity DataIC50: 11nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM152479(Z-L-Am7(Ac)-QA (1))
Affinity DataIC50: 18nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM152480(Z-L-Am7(AcEtMe)-QA (2))
Affinity DataIC50: 18nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM152480(Z-L-Am7(AcEtMe)-QA (2))
Affinity DataIC50: 19nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM152480(Z-L-Am7(AcEtMe)-QA (2))
Affinity DataIC50: 29nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM152479(Z-L-Am7(Ac)-QA (1))
Affinity DataIC50: 34nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM50200895((S)-benzyl 8-(hydroxyamino)-1,8-dioxo-1-(quinolin-...)
Affinity DataIC50: 45nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM152479(Z-L-Am7(Ac)-QA (1))
Affinity DataIC50: 47nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 270nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 290nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 340nMAssay Description:For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed