Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50046690
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342583((E)-4-chloro-3-(2-(2-methoxyphenyl)-2-oxoethyliden...)
Affinity DataKi:  3.30E+3nMAssay Description:Non-competitive inhibition of recombinant human TG2 V224 mutant deamidation activity using Cbz-Gln-Gly as substrate preincubated for 30 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342590((E)-4-chloro-3-(2-oxo-2-(pyridin-3-yl)ethylidene)-...)
Affinity DataKi:  9.10E+3nMAssay Description:Non-competitive inhibition of recombinant human TG2 V224 mutant deamidation activity using Cbz-Gln-Gly as substrate preincubated for 30 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM81791(Guanylyl imidodiphosphate | GPP(NH)p(-) | GPP(NH)P...)
Affinity DataKi:  2.70E+4nMAssay Description:Competitive inhibition of recombinant human TG2 V224 mutant deamidation activity using Cbz-Gln-Gly as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342582((E)-4-chloro-3-(2-(4-chlorophenyl)-2-oxoethylidene...)
Affinity DataKi:  4.70E+4nMAssay Description:Non-competitive inhibition of recombinant human TG2 V224 mutant deamidation activity using Cbz-Gln-Gly as substrate preincubated for 30 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342569((E)-3-(2-oxo-2-(pyridin-3-yl)ethylidene)indolin-2-...)
Affinity DataKi:  8.60E+4nMAssay Description:Non-competitive inhibition of recombinant human TG2 V224 mutant deamidation activity using Cbz-Gln-Gly as substrate preincubated for 30 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed