Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50046100
TargetMelanin-concentrating hormone receptor 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50094884(CHEMBL3589154)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50241083(6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50094880(CHEMBL3589145)
Affinity DataIC50: 241nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50094882(CHEMBL3589135)
Affinity DataIC50: 1.17E+3nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50094883(CHEMBL3589138)
Affinity DataIC50: 3.06E+3nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50094879(CHEMBL3589153)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated whole-cell patch clamp electrophysiology systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50094878(CHEMBL3589152)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated whole-cell patch clamp electrophysiology systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50241083(6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1...)
Affinity DataKi:  0.340nMAssay Description:Antagonist activity at rat MCHR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50094880(CHEMBL3589145)
Affinity DataKi:  0.800nMAssay Description:Antagonist activity at rat MCHR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50094885(CHEMBL3588863)
Affinity DataKi:  3.80nMAssay Description:Antagonist activity at rat MCHR1 assessed as 2-(4-chlorophenyl)-5-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50094881(CHEMBL3589155)
Affinity DataKi:  7.20nMAssay Description:Antagonist activity at rat MCHR1 assessed as 6-(4-chlorophenyl)-3-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)thieno[3,2-d]pyrimidin-4(3H)-oneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed