Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50046187
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098412(CHEMBL3593400)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098413(CHEMBL3593399)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098373(CHEMBL3593395)
Affinity DataIC50: 2nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098387(CHEMBL3593274)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098410(CHEMBL3593402)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098408(CHEMBL3593404)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098407(CHEMBL3593405)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098376(CHEMBL3593392)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098372(CHEMBL3593396)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098411(CHEMBL3593401)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098374(CHEMBL3593394)
Affinity DataIC50: 6nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098375(CHEMBL3593393)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098375(CHEMBL3593393)
Affinity DataIC50: 11nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098370(CHEMBL3593398)
Affinity DataIC50: 12nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098409(CHEMBL3593403)
Affinity DataIC50: 13nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098384(CHEMBL3593275)
Affinity DataIC50: 17nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098387(CHEMBL3593274)
Affinity DataIC50: 35nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098372(CHEMBL3593396)
Affinity DataIC50: 36nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098371(CHEMBL3593397)
Affinity DataIC50: 52nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098413(CHEMBL3593399)
Affinity DataIC50: 70nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098373(CHEMBL3593395)
Affinity DataIC50: 97nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098374(CHEMBL3593394)
Affinity DataIC50: 120nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098412(CHEMBL3593400)
Affinity DataIC50: 150nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098376(CHEMBL3593392)
Affinity DataIC50: 200nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098384(CHEMBL3593275)
Affinity DataIC50: 200nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098411(CHEMBL3593401)
Affinity DataIC50: 200nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098377(CHEMBL3593391)
Affinity DataIC50: 330nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098413(CHEMBL3593399)
Affinity DataIC50: 350nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098408(CHEMBL3593404)
Affinity DataIC50: 480nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098407(CHEMBL3593405)
Affinity DataIC50: 680nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098377(CHEMBL3593391)
Affinity DataIC50: 700nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098371(CHEMBL3593397)
Affinity DataIC50: 780nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098409(CHEMBL3593403)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098387(CHEMBL3593274)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098408(CHEMBL3593404)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098407(CHEMBL3593405)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098375(CHEMBL3593393)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098374(CHEMBL3593394)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098370(CHEMBL3593398)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098370(CHEMBL3593398)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098411(CHEMBL3593401)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098410(CHEMBL3593402)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098410(CHEMBL3593402)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098409(CHEMBL3593403)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098372(CHEMBL3593396)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098412(CHEMBL3593400)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098373(CHEMBL3593395)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098384(CHEMBL3593275)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098377(CHEMBL3593391)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098376(CHEMBL3593392)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
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