Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50046188
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098418(CHEMBL3593409)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098418(CHEMBL3593409)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098418(CHEMBL3593409)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50322422(Largazole | CHEMBL1173445)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50322422(Largazole | CHEMBL1173445)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098424(CHEMBL3593415)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098424(CHEMBL3593415)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50322422(Largazole | CHEMBL1173445)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098424(CHEMBL3593415)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098422(CHEMBL3593413)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098422(CHEMBL3593413)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098418(CHEMBL3593409)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098422(CHEMBL3593413)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50: 102nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50: 102nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50322422(Largazole | CHEMBL1173445)
Affinity DataIC50: 166nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098417(CHEMBL3593408)
Affinity DataIC50: 204nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50: 228nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50: 255nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098419(CHEMBL3593410)
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098417(CHEMBL3593408)
Affinity DataIC50: 332nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098421(CHEMBL3593412)
Affinity DataIC50: 332nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098419(CHEMBL3593410)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098421(CHEMBL3593412)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098418(CHEMBL3593409)
Affinity DataIC50: 341nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098417(CHEMBL3593408)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098421(CHEMBL3593412)
Affinity DataIC50: 472nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098415(CHEMBL3593406)
Affinity DataIC50: 544nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098419(CHEMBL3593410)
Affinity DataIC50: 655nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098423(CHEMBL3593414)
Affinity DataIC50: 817nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098415(CHEMBL3593406)
Affinity DataIC50: 825nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098423(CHEMBL3593414)
Affinity DataIC50: 847nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50322422(Largazole | CHEMBL1173445)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098415(CHEMBL3593406)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098423(CHEMBL3593414)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098424(CHEMBL3593415)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098424(CHEMBL3593415)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed