Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50046106
TargetBeta-secretase 1(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM50210579((2S,5S,8S,11R,13S,14S,17S,20S,23S)-23-amino-2-benz...)
Affinity DataKi:  0.310nMAssay Description:Inhibition of active BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM50210579((2S,5S,8S,11R,13S,14S,17S,20S,23S)-23-amino-2-benz...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant BACE1 using Mca-SEVNLDAEFK-DNP substrate assessed as substrate hydrolysis after 2 hrs by HPLC-FLU analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM16047(EVNXXAEF | N-{(2R,4S,5S)-5-[(L-alpha-glutamyl-L-va...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of active BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM50094979(CHEMBL3589002)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human recombinant BACE1 using Mca-SEVNLDAEFK-DNP substrate assessed as substrate hydrolysis after 2 hrs by HPLC-FLU analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM50094977(CHEMBL3589000)
Affinity DataKi:  1.90nMAssay Description:Inhibition of human recombinant BACE1 using Mca-SEVNLDAEFK-DNP substrate assessed as substrate hydrolysis after 2 hrs by HPLC-FLU analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM50094976(CHEMBL3588999)
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant BACE1 using Mca-SEVNLDAEFK-DNP substrate assessed as substrate hydrolysis after 2 hrs by HPLC-FLU analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM50094978(CHEMBL3589001)
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant BACE1 using Mca-SEVNLDAEFK-DNP substrate assessed as substrate hydrolysis after 2 hrs by HPLC-FLU analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM50210579((2S,5S,8S,11R,13S,14S,17S,20S,23S)-23-amino-2-benz...)
Affinity DataKi:  3nMAssay Description:Apparent inhibition of human recombinant BACE2 using Mca-SEVNLDAEFK-DNP substrate assessed as substrate hydrolysis after 1 hr by HPLC-FLU analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM50094976(CHEMBL3588999)
Affinity DataKi:  7.30nMAssay Description:Apparent inhibition of human recombinant BACE2 using Mca-SEVNLDAEFK-DNP substrate assessed as substrate hydrolysis after 1 hr by HPLC-FLU analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM16047(EVNXXAEF | N-{(2R,4S,5S)-5-[(L-alpha-glutamyl-L-va...)
Affinity DataKi:  9.80nMAssay Description:Inhibition of pro-BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM50094979(CHEMBL3589002)
Affinity DataKi:  13nMAssay Description:Apparent inhibition of human recombinant BACE2 using Mca-SEVNLDAEFK-DNP substrate assessed as substrate hydrolysis after 1 hr by HPLC-FLU analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM50094977(CHEMBL3589000)
Affinity DataKi:  14nMAssay Description:Apparent inhibition of human recombinant BACE2 using Mca-SEVNLDAEFK-DNP substrate assessed as substrate hydrolysis after 1 hr by HPLC-FLU analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Instituto De Biologia Experimental E Tecnol£Gica

Curated by ChEMBL
LigandPNGBDBM50094978(CHEMBL3589001)
Affinity DataKi:  18nMAssay Description:Apparent inhibition of human recombinant BACE2 using Mca-SEVNLDAEFK-DNP substrate assessed as substrate hydrolysis after 1 hr by HPLC-FLU analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed