Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 7050
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170126(4-(3-(4-Phenyl ethyl oxygen)-5-(2-hydroxyphenyl)-4...)
Affinity DataIC50: 330nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170149((4aS,5aS,6S,12aR)-1,6,10,11,12a-pentahydroxy-6-met...)
Affinity DataIC50: 1.13E+3nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170128(4-(5-(2-Hydroxyphenyl)-3-(3-oxygen methyl phenyl)-...)
Affinity DataIC50: 1.81E+3nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170148(4-(5-(2-Hydroxyphenyl)-3-(4-methoxy phenyl)-4, 5-d...)
Affinity DataIC50: 1.83E+3nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170139(4-(5-(5-Chloro-2-hydroxyphenyl)-3-(3-oxygen methyl...)
Affinity DataIC50: 2.13E+3nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170141(4-(5-(5-Bromine-2-hydroxyphenyl)-3-(3-oxygen methy...)
Affinity DataIC50: 3.23E+3nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170138(4-(5-(5-Chloro-2-hydroxyphenyl)-3-(4-phenyl ethyl ...)
Affinity DataIC50: 3.84E+3nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170135(-(5-(5-Chloro-2-hydroxyphenyl)-3-(4-methyl phenyl ...)
Affinity DataIC50: 4.62E+3nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170129(4-(3-(3, 4-Dimethyl phenyl)-5-(2-hydroxyphenyl)-4,...)
Affinity DataIC50: 4.65E+3nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170145(4-(5-(5-Bromine-2-hydroxyphenyl)-3-(4-bromine phen...)
Affinity DataIC50: 8.73E+3nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170131(4-(5-(5-Chloro-2-hydroxyphenyl)-3-(4-phenyl)-4, 5-...)
Affinity DataIC50: 8.83E+3nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170124(4-(5-(2-Hydroxyphenyl)-3-phenyl-4, 5-dihydro pyraz...)
Affinity DataIC50: 9.83E+3nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170134(4-(5-(5-Chloro-2-hydroxyphenyl)-3-(4-chlorobenzene...)
Affinity DataIC50: 1.13E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170125(4-(3-(2-Chlorobenzene)-5-(2-hydroxyphenyl)-4, 5-di...)
Affinity DataIC50: 1.15E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170140(4-(5-(5-Bromine-2-hydroxyphenyl)-3-phenyl-4, 5-dih...)
Affinity DataIC50: 1.28E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170130(4-(3-(3, 4-Dichlorobenzene base)-5-(2-hydroxypheny...)
Affinity DataIC50: 1.29E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170133(4-(5-(5-Chloro-2-hydroxyphenyl)-3-phenyl)-4, 5-dih...)
Affinity DataIC50: 1.35E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170143(4-(5-(5-Bromine-2-hydroxyphenyl)-3-(2-chlorobenzen...)
Affinity DataIC50: 1.50E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170144(4-(5-(5-Bromine-2-hydroxyphenyl)-3-(4-chlorobenzen...)
Affinity DataIC50: 1.58E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170146(4-(5-(5-Bromine-2-hydroxyphenyl)-3-(3, 4-dichlorob...)
Affinity DataIC50: 1.62E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170132(4-(5-(5-Chloro-2-hydroxyphenyl) -3 - (2 - chlorobe...)
Affinity DataIC50: 1.64E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170137(4-(5-(5-Chloro-2-hydroxyphenyl)-3-(3, 4-dichlorobe...)
Affinity DataIC50: 1.65E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM60599(4-(5-(5-Bromine-2-hydroxyphenyl)-3-(4-phenyl)-4, 5...)
Affinity DataIC50: 1.73E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170127(4-(3-(4-Bromine phenyl)-5-(2-hydroxyphenyl)-4, 5-d...)
Affinity DataIC50: 1.88E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170136(4-(3-(4-Bromine phenyl)-5-(5-chloro-2-hydroxypheny...)
Affinity DataIC50: 1.89E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170147(4-(5-(2-Hydroxyphenyl)-3-(4-fluorinated phenyl)-4,...)
Affinity DataIC50: 2.47E+4nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed