Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 50046400
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity against human P2X7 receptor assessed as inhibition of IL-1beta production by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at P2X7 receptor in human whole blood assessed as inhibition of BzATP-induced IL1beta release incubated 30 mins prior to BzATP-ch...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at P2X7 receptor in human whole blood assessed as inhibition of BzATP-induced IL1beta release incubated 30 mins prior to BzATP-ch...More data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity against human P2X7 receptor expressed in HEK293 cells by FLIPR based calcium accumulation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity against human P2X7 receptor expressed in HEK293 cells by FLIPR based calcium accumulation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at P2X7 receptor in human whole blood assessed as inhibition of BzATP-induced IL1beta release incubated 30 mins prior to BzATP-ch...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Antagonist activity at P2X7 receptor in human whole blood assessed as inhibition of BzATP-induced IL1beta release incubated 30 mins prior to BzATP-ch...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 182nMAssay Description:Antagonist activity at P2X7 receptor in human whole blood assessed as inhibition of BzATP-induced IL1beta release incubated 30 mins prior to BzATP-ch...More data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+3nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
