Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50046139
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM13469(({4-[(2S)-2-carbamoyl-2-[(2S)-2-(1-{4-[difluoro(ph...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human PTP1B catalytic domain expressed in Escherichia coli assessed as pNPP hydrolysis measured every 30 secs for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50096221(CHEMBL3593819)
Affinity DataIC50: 203nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50096225(CHEMBL3593821)
Affinity DataIC50: 204nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50096222(CHEMBL3593818)
Affinity DataIC50: 212nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50096223(CHEMBL3593817)
Affinity DataIC50: 309nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50096227(CHEMBL3593816)
Affinity DataIC50: 537nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50096224(CHEMBL3593822)
Affinity DataIC50: 756nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50096222(CHEMBL3593818)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50096222(CHEMBL3593818)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50096226(CHEMBL3593820)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50096223(CHEMBL3593817)
Affinity DataIC50: 5.19E+3nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 5.46E+3nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50096221(CHEMBL3593819)
Affinity DataIC50: 9.08E+3nMAssay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of SHP2 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of LAR (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed