Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50046349
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50107339(CHEMBL3601294)
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142183(US8933079, 5.2)
Affinity DataIC50: 8.70nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50107335(CHEMBL3601303)
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50107338(CHEMBL3601295)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142217(US8933079, 8.3)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142115(US8933079, 4.1)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142134(US8933079, 1.8)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142122(US8933079, 149 | US8933079, 150 | US8933079, 9.1)
Affinity DataIC50: 18nMAssay Description:Binding affinity to rat MCH-R1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50107323(CHEMBL3601375)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142122(US8933079, 149 | US8933079, 150 | US8933079, 9.1)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142215(US8933079, 7.16)
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50107324(CHEMBL3601373)
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50107336(CHEMBL3601299)
Affinity DataIC50: 28nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142156(US8933079, 3.9)
Affinity DataIC50: 33nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50107337(CHEMBL3601297)
Affinity DataIC50: 41nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142230(US8933079, 11.2)
Affinity DataIC50: 57nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142147(US8933079, 2.5)
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142122(US8933079, 149 | US8933079, 150 | US8933079, 9.1)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142122(US8933079, 149 | US8933079, 150 | US8933079, 9.1)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142122(US8933079, 149 | US8933079, 150 | US8933079, 9.1)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142122(US8933079, 149 | US8933079, 150 | US8933079, 9.1)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142122(US8933079, 149 | US8933079, 150 | US8933079, 9.1)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142122(US8933079, 149 | US8933079, 150 | US8933079, 9.1)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM142122(US8933079, 149 | US8933079, 150 | US8933079, 9.1)
Affinity DataKi:  14nMAssay Description:Binding affinity to human MCH-R1 expressed in CHO/Galpha16 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed