Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50046466
TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114071(CHEMBL3604009)
Affinity DataEC50:  496nMAssay Description:Binding affinity to DAT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114071(CHEMBL3604009)
Affinity DataEC50:  347nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114072(CHEMBL3603954)
Affinity DataEC50:  597nMAssay Description:Binding affinity to DAT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114072(CHEMBL3603954)
Affinity DataEC50:  117nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114073(CHEMBL3604010 | US20240327372, Compound Racemic me...)
Affinity DataEC50:  133nMAssay Description:Binding affinity to DAT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114073(CHEMBL3604010 | US20240327372, Compound Racemic me...)
Affinity DataEC50:  242nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50010588(DL-(3,4-Methylenedioxy)methamphetamine | N-Methyl-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Binding affinity to human NET expressed in HEK293 cells assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50010588(DL-(3,4-Methylenedioxy)methamphetamine | N-Methyl-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Binding affinity to human DAT expressed in HEK293 cells assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50010588(DL-(3,4-Methylenedioxy)methamphetamine | N-Methyl-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Binding affinity to human SERT expressed in HEK293 cells assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50010588(DL-(3,4-Methylenedioxy)methamphetamine | N-Methyl-...)
Affinity DataEC50:  75nMAssay Description:Binding affinity to DAT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50010588(DL-(3,4-Methylenedioxy)methamphetamine | N-Methyl-...)
Affinity DataEC50:  61nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114074(CHEMBL3603955)
Affinity DataEC50:  276nMAssay Description:Binding affinity to DAT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114074(CHEMBL3603955)
Affinity DataEC50:  91nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114075(CHEMBL3603956)
Affinity DataEC50:  1.46E+4nMAssay Description:Binding affinity to DAT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114075(CHEMBL3603956)
Affinity DataEC50:  573nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed