Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50046642
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM35909(Eulexin | 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50123007(CHEMBL3622589)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122954(CHEMBL3622579)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122953(CHEMBL3622578)
Affinity DataIC50: 530nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50123010(CHEMBL3622590)
Affinity DataIC50: 920nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122957(CHEMBL3622581)
Affinity DataIC50: 1.01E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50183678(4-(2-chlorobenzyl)phthalazin-1(2H)-one | CHEMBL378...)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122962(CHEMBL3622587)
Affinity DataIC50: 1.38E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122958(CHEMBL3622583)
Affinity DataIC50: 1.66E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122960(CHEMBL3622585)
Affinity DataIC50: 1.95E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122952(CHEMBL3622576)
Affinity DataIC50: 3.67E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122959(CHEMBL3622584)
Affinity DataIC50: 3.71E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50123006(CHEMBL3622588)
Affinity DataIC50: 3.76E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM27660(CHEMBL66761 | 4-benzyl-1,2-dihydrophthalazin-1-one...)
Affinity DataIC50: 5.37E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM35909(Eulexin | 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...)
Affinity DataIC50: 7.69E+3nMAssay Description:Displacement of [3H]-DHT from human GST fused AR-LBD (627 to 919 amino acids) transfected in Escherichia coli HB 101 after 15 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122961(CHEMBL3622586)
Affinity DataIC50: 9.02E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122949(CHEMBL3622573)
Affinity DataIC50: 9.54E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122950(CHEMBL3622574)
Affinity DataIC50: 9.59E+3nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122951(CHEMBL3622575)
Affinity DataIC50: 1.05E+4nMAssay Description:Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50123007(CHEMBL3622589)
Affinity DataIC50: 1.09E+4nMAssay Description:Displacement of [3H]-DHT from human GST fused AR-LBD (627 to 919 amino acids) transfected in Escherichia coli HB 101 after 15 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122954(CHEMBL3622579)
Affinity DataIC50: 4.52E+4nMAssay Description:Displacement of [3H]-DHT from human GST fused AR-LBD (627 to 919 amino acids) transfected in Escherichia coli HB 101 after 15 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50123010(CHEMBL3622590)
Affinity DataIC50: 5.67E+4nMAssay Description:Displacement of [3H]-DHT from human GST fused AR-LBD (627 to 919 amino acids) transfected in Escherichia coli HB 101 after 15 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122962(CHEMBL3622587)
Affinity DataIC50: 8.43E+4nMAssay Description:Displacement of [3H]-DHT from human GST fused AR-LBD (627 to 919 amino acids) transfected in Escherichia coli HB 101 after 15 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50183678(4-(2-chlorobenzyl)phthalazin-1(2H)-one | CHEMBL378...)
Affinity DataIC50: 8.54E+4nMAssay Description:Displacement of [3H]-DHT from human GST fused AR-LBD (627 to 919 amino acids) transfected in Escherichia coli HB 101 after 15 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50122953(CHEMBL3622578)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]-DHT from human GST fused AR-LBD (627 to 919 amino acids) transfected in Escherichia coli HB 101 after 15 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed