Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50046586
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120437(CHEMBL3617973 | US12415819, Compound 54)
Affinity DataKi:  0.0800nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50118028(3-Isopropyl-1-methanesulfonyl-4-(2-pyrrolidin-1-yl...)
Affinity DataKi:  0.160nMAssay Description:Inhibition of neutrophil elastase in human whole blood using MeO-Succ-Ala-Ala-Pro-Val-pNA as substrate after 30 mins by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50035500(1-{2-[4-(4-Chloro-benzenesulfonylaminocarbonyl)-be...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of neutrophil elastase in human whole blood using MeO-Succ-Ala-Ala-Pro-Val-pNA as substrate after 30 mins by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120428(CHEMBL3617966)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120436(CHEMBL3617972)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120429(CHEMBL3617965)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120424(CHEMBL3617970)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120438(US9290459, 23 | US9670166, 23 | CHEMBL3617974)
Affinity DataIC50: 1nMAssay Description:Inhibition of neutrophil elastase in human plasma using MeOSuc-Ala-Ala-Pro-Val-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120438(US9290459, 23 | US9670166, 23 | CHEMBL3617974)
Affinity DataIC50: 1nMAssay Description:Inhibition of human neutrophil elastase using MeO-Succ-Ala-Ala-Pro-Val-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120439(US9290459, 47.1 | US9670166, 47.1 | CHEMBL3617975)
Affinity DataIC50: 1nMAssay Description:Inhibition of neutrophil elastase in human plasma using MeOSuc-Ala-Ala-Pro-Val-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120439(US9290459, 47.1 | US9670166, 47.1 | CHEMBL3617975)
Affinity DataIC50: 1nMAssay Description:Inhibition of human neutrophil elastase using MeO-Succ-Ala-Ala-Pro-Val-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120440(CHEMBL3617976)
Affinity DataIC50: 1nMAssay Description:Inhibition of neutrophil elastase in human plasma using MeOSuc-Ala-Ala-Pro-Val-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120440(CHEMBL3617976)
Affinity DataIC50: 1nMAssay Description:Inhibition of human neutrophil elastase using MeO-Succ-Ala-Ala-Pro-Val-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120425(CHEMBL3617969)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120434(CHEMBL3617961)
Affinity DataIC50: 7nMAssay Description:Inhibition of neutrophil elastase in human whole blood using MeO-Succ-Ala-Ala-Pro-Val-pNA as substrate after 30 mins by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120430(CHEMBL3617964 | US12415819, Compound 53)
Affinity DataKi:  12nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val 7-amido-4-methylcoumarin as substrate preincubated for 15 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50095522(ONO-6818 | 2-(5-amino-6-oxo-2-phenylpyrimidin-1(6H...)
Affinity DataKi:  12nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120426(CHEMBL3617968)
Affinity DataKi:  15nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120431(CHEMBL3617963)
Affinity DataIC50: 17nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120427(CHEMBL3617967)
Affinity DataIC50: 20nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120454(CHEMBL3617977)
Affinity DataIC50: 20nMAssay Description:Inhibition of human neutrophil elastase using MeO-Succ-Ala-Ala-Pro-Val-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50118029(3-Isopropyl-1-methanesulfonyl-4-(4-piperidin-1-yl-...)
Affinity DataIC50: 22nMAssay Description:Inhibition of neutrophil elastase in human whole blood using MeO-Succ-Ala-Ala-Pro-Val-pNA as substrate after 30 mins by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120423(US9290459, 1A | US9670166, 1A | CHEMBL3617971)
Affinity DataIC50: 22nMAssay Description:Inhibition of neutrophil elastase in human plasma using MeOSuc-Ala-Ala-Pro-Val-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120423(US9290459, 1A | US9670166, 1A | CHEMBL3617971)
Affinity DataIC50: 22nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120432(CHEMBL3617962)
Affinity DataIC50: 44nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120433(ONO-5046.NA | Sivelestat Sodium)
Affinity DataKi:  200nMAssay Description:Inhibition of human neutrophil elastase using suc-Ala-Pro-Ala-pNA as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50349435(CHEMBL1808549)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of neutrophil elastase in human whole blood using MeO-Succ-Ala-Ala-Pro-Val-pNA as substrate after 30 mins by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed