Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50046677
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CYP11B2 expressed in renal leiomyoblastoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human CYP11B2 expressed in renal leiomyoblastoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125049(CHEMBL3623830)
Affinity DataIC50: 9nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191903(US9187429, 38 | US9187429, 37 | US9187429, 36)
Affinity DataIC50: 14nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191882(US9187429, 8)
Affinity DataIC50: 21nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191880(US9187429, 7 | US9187429, 6 | US9187429, 5)
Affinity DataIC50: 25nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191908(US9187429, 43)
Affinity DataIC50: 27nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191899(US9187429, 32 | US9187429, 31 | US9187429, 30)
Affinity DataIC50: 28nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125051(CHEMBL3623821)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191876(US9187429, 1)
Affinity DataIC50: 42nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191909(US9187429, 44)
Affinity DataIC50: 47nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191883(US9187429, 9)
Affinity DataIC50: 123nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 190nMAssay Description:Inhibition of mouse CYP11B2 expressed in renal leiomyoblastoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)
Affinity DataIC50: 210nMAssay Description:Inhibition of mouse CYP11B2 expressed in renal leiomyoblastoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125049(CHEMBL3623830)
Affinity DataIC50: 530nMAssay Description:Inhibition of mouse CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125050(CHEMBL3623831)
Affinity DataIC50: 942nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Mouse)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125050(CHEMBL3623831)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125050(CHEMBL3623831)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125050(CHEMBL3623831)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125050(CHEMBL3623831)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125049(CHEMBL3623830)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191883(US9187429, 9)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191882(US9187429, 8)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191880(US9187429, 7 | US9187429, 6 | US9187429, 5)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191883(US9187429, 9)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125049(CHEMBL3623830)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191882(US9187429, 8)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191882(US9187429, 8)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191880(US9187429, 7 | US9187429, 6 | US9187429, 5)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191883(US9187429, 9)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125049(CHEMBL3623830)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Roche Pharma Research and Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191880(US9187429, 7 | US9187429, 6 | US9187429, 5)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed