Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50046781
TargetSerine protease hepsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130870(CHEMBL3632759)
Affinity DataKi:  100nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130874(CHEMBL3632761)
Affinity DataKi:  100nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130870(CHEMBL3632759)
Affinity DataKi:  400nMAssay Description:Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130871(CHEMBL3632760)
Affinity DataKi:  400nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130871(CHEMBL3632760)
Affinity DataKi:  500nMAssay Description:Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130868(CHEMBL3632757)
Affinity DataKi:  500nMAssay Description:Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130869(CHEMBL3632758)
Affinity DataKi:  600nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130871(CHEMBL3632760)
Affinity DataKi:  700nMAssay Description:Inhibition of bovine factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130874(CHEMBL3632761)
Affinity DataKi:  800nMAssay Description:Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130866(CHEMBL3632755)
Affinity DataKi:  800nMAssay Description:Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130871(CHEMBL3632760)
Affinity DataKi:  800nMAssay Description:Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130866(CHEMBL3632755)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of bovine factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130874(CHEMBL3632761)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130870(CHEMBL3632759)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130868(CHEMBL3632757)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130870(CHEMBL3632759)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of bovine factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130869(CHEMBL3632758)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130866(CHEMBL3632755)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130870(CHEMBL3632759)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130870(CHEMBL3632759)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130869(CHEMBL3632758)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50102768(2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50102768(2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130871(CHEMBL3632760)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130871(CHEMBL3632760)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130866(CHEMBL3632755)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130867(CHEMBL3632756)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130867(CHEMBL3632756)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130866(CHEMBL3632755)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50100897(2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}BE...)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130874(CHEMBL3632761)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50102768(2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130874(CHEMBL3632761)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of bovine factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50130874(CHEMBL3632761)
Affinity DataKi:  8.60E+3nMAssay Description:Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetPlasminogen(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50102768(2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of human plasmin by fluorescence based assay using pyroGlu-Phe-Lys-pNA.HCl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50102768(2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50100897(2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}BE...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of bovine factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50100897(2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}BE...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50102768(2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50100897(2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}BE...)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetPlasminogen(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50100897(2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}BE...)
Affinity DataKi:  4.60E+4nMAssay Description:Inhibition of human plasmin by fluorescence based assay using pyroGlu-Phe-Lys-pNA.HCl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50100897(2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}BE...)
Affinity DataKi:  5.50E+4nMAssay Description:Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50102768(2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...)
Affinity DataKi:  6.00E+4nMAssay Description:Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50027306(1H-Indole-5-carboxamidine | CHEMBL26490)
Affinity DataKi:  5.00E+5nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed