Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50006349
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PARP1 in human G7 cells incubated for 60 mins by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PARP1 in human T98G cells incubated for 60 mins by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499078(CHEMBL3735519)
Affinity DataIC50: 3nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499076(CHEMBL3735979)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499080(CHEMBL3736047)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499075(CHEMBL3735832)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499076(CHEMBL3735979)
Affinity DataIC50: 7nMAssay Description:Inhibition of PARP1 in human G7 cells incubated for 60 mins by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499076(CHEMBL3735979)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of PARP1 in human T98G cells incubated for 60 mins by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 12nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499081(CHEMBL3735916)
Affinity DataIC50: 17nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499079(CHEMBL3735363)
Affinity DataIC50: 18nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499077(CHEMBL3736506)
Affinity DataIC50: 23nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed