Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50046739
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128830(CHEMBL3629353)
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHO cells assessed as stumulation of intracellular cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM25771(salmeterol xinafoate | 4-(1-hydroxy-2-{[6-(4-pheny...)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig trachea assessed as inhibition of histamine-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128835(CHEMBL3629360)
Affinity DataEC50:  13nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig trachea assessed as inhibition of histamine-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128835(CHEMBL3629360)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHO cells assessed as stumulation of intracellular cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128834(CHEMBL3629359)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHO cells assessed as stumulation of intracellular cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128832(CHEMBL3629357)
Affinity DataEC50:  116nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHO cells assessed as stumulation of intracellular cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128833(CHEMBL3629358)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHO cells assessed as stumulation of intracellular cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343161(5-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phen...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHO cells assessed as stumulation of intracellular cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128831(CHEMBL3629356)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHO cells assessed as stumulation of intracellular cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128835(CHEMBL3629360)
Affinity DataKi:  0.140nMAssay Description:Antagonist activity at muscarinic M2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128835(CHEMBL3629360)
Affinity DataKi:  0.160nMAssay Description:Antagonist activity at muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128835(CHEMBL3629360)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343161(5-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phen...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128837(CHEMBL3629354)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128835(CHEMBL3629360)
Affinity DataKi:  0.350nMAssay Description:Antagonist activity at muscarinic M4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128830(CHEMBL3629353)
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128835(CHEMBL3629360)
Affinity DataKi:  1.10nMAssay Description:Antagonist activity at muscarinic M5 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128836(CHEMBL143228)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128838(CHEMBL3629355)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128831(CHEMBL3629356)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128834(CHEMBL3629359)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128833(CHEMBL3629358)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128832(CHEMBL3629357)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed