Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50006406
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499753(CHEMBL3741471)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499733(CHEMBL3740378)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499738(CHEMBL3740153)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499736(CHEMBL3740601)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499745(CHEMBL3741267)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499754(CHEMBL3740253)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499741(CHEMBL3739994)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499730(CHEMBL3740368)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499746(CHEMBL3739537)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499734(CHEMBL3741072)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499735(CHEMBL3740206)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499750(CHEMBL3741002)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499740(CHEMBL3740166)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499737(CHEMBL3741594)
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499751(CHEMBL3742051)
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499727(CHEMBL3740719)
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499732(CHEMBL3742365)
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499755(CHEMBL3741666)
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499752(CHEMBL3740086)
Affinity DataIC50: 121nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499742(CHEMBL3739853)
Affinity DataIC50: 169nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499729(CHEMBL3739555)
Affinity DataIC50: 269nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499749(CHEMBL3741126)
Affinity DataIC50: 282nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499747(CHEMBL3739710)
Affinity DataIC50: 332nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499748(CHEMBL3742218)
Affinity DataIC50: 593nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499744(CHEMBL3740796)
Affinity DataIC50: 969nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499728(CHEMBL3742323)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499739(CHEMBL3742108)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499743(CHEMBL3741394)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLegumain(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499731(CHEMBL3741481)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499736(CHEMBL3740601)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant caspase 3 (unknown origin) using DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCathepsin S(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499737(CHEMBL3741594)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant cathepsin S (unknown origin) using ZVVR-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499736(CHEMBL3740601)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant cathepsin B (unknown origin) using Z-Leu-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499737(CHEMBL3741594)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant cathepsin B (unknown origin) using Z-Leu-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499738(CHEMBL3740153)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant caspase 3 (unknown origin) using DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCaspase-3(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499737(CHEMBL3741594)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant caspase 3 (unknown origin) using DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCaspase-8(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499738(CHEMBL3740153)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant caspase 8 (unknown origin) using IETD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 17(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499736(CHEMBL3740601)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of USP17 in human HEK293T cells using fluorogenic substrate ub-rhodamine110 preincubated for 30 mins followed by substrate addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 17(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499738(CHEMBL3740153)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of USP17 in human HEK293T cells using fluorogenic substrate ub-rhodamine110 preincubated for 30 mins followed by substrate addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCaspase-8(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499736(CHEMBL3740601)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant caspase 8 (unknown origin) using IETD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499738(CHEMBL3740153)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant cathepsin B (unknown origin) using Z-Leu-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCathepsin S(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499736(CHEMBL3740601)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant cathepsin S (unknown origin) using ZVVR-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 17(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499737(CHEMBL3741594)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of USP17 in human HEK293T cells using fluorogenic substrate ub-rhodamine110 preincubated for 30 mins followed by substrate addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCathepsin S(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499738(CHEMBL3740153)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant cathepsin S (unknown origin) using ZVVR-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCaspase-8(Human)
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499737(CHEMBL3741594)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant caspase 8 (unknown origin) using IETD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed