Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50006548
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500800(CHEMBL3758973)
Affinity DataEC50:  683nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced beta-arrestin recruitment p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500802(CHEMBL3758782)
Affinity DataEC50:  209nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced beta-arrestin recruitment p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50389939(CHEMBL1553629)
Affinity DataEC50:  83nMAssay Description:Positive allosteric modulator activity at human CB1R expressed in CHO cells assessed as enhanced binding of [3H]CP55,940 after 60 mins by liquid scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500805(CHEMBL3759542)
Affinity DataEC50:  118nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50389939(CHEMBL1553629)
Affinity DataEC50:  9.10nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced beta-arrestin recruitment p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500804(CHEMBL3758817)
Affinity DataEC50:  28nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced beta-arrestin recruitment p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500799(CHEMBL3758877)
Affinity DataEC50:  2.10nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced beta-arrestin recruitment p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500803(CHEMBL3758424)
Affinity DataEC50:  64nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced beta-arrestin recruitment p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50023629(CHEMBL3341861)
Affinity DataEC50:  3.80nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced beta-arrestin recruitment p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500801(CHEMBL3758325)
Affinity DataEC50:  28nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced beta-arrestin recruitment p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500805(CHEMBL3759542)
Affinity DataEC50:  43nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced beta-arrestin recruitment p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50023629(CHEMBL3341861)
Affinity DataEC50:  71nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500804(CHEMBL3758817)
Affinity DataEC50:  389nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500803(CHEMBL3758424)
Affinity DataEC50:  1.12E+3nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500802(CHEMBL3758782)
Affinity DataEC50: >1.00E+4nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500801(CHEMBL3758325)
Affinity DataEC50:  166nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500800(CHEMBL3758973)
Affinity DataEC50: >1.00E+4nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  4.90nMAssay Description:Positive allosteric modulator activity at human CB1R expressed in CHO cells assessed as enhanced binding of [3H]CP55,940 after 60 mins by liquid scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50389939(CHEMBL1553629)
Affinity DataEC50:  324nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500799(CHEMBL3758877)
Affinity DataEC50:  20nMAssay Description:Positive allosteric modulator activity at human CB1R expressed in CHO cells assessed as enhanced binding of [3H]CP55,940 after 60 mins by liquid scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500799(CHEMBL3758877)
Affinity DataEC50:  27nMAssay Description:Activity at CB1R in mouse brain membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding preincubated for 60 mins prior to [35S]GT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50500799(CHEMBL3758877)
Affinity DataEC50:  174nMAssay Description:Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed