Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50006367
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499218(CHEMBL3735684)
Affinity DataEC50:  5nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499221(CHEMBL3736161)
Affinity DataEC50:  5nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499226(CHEMBL3734885)
Affinity DataEC50:  10nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499229(CHEMBL3735704)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499224(CHEMBL3735720)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499222(CHEMBL3736277)
Affinity DataEC50:  20nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499225(CHEMBL3735762)
Affinity DataEC50:  32nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499216(CHEMBL3736345)
Affinity DataEC50:  50nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499234(CHEMBL3735340)
Affinity DataEC50:  79nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499232(CHEMBL3736066)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499219(CHEMBL3735325)
Affinity DataEC50:  398nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499227(CHEMBL3735872)
Affinity DataEC50:  398nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499219(CHEMBL3735325)
Affinity DataEC50:  398nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499236(CHEMBL3735905)
Affinity DataEC50:  398nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499235(CHEMBL3736335)
Affinity DataEC50:  398nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499230(CHEMBL3736168)
Affinity DataEC50:  1.00E+3nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499217(CHEMBL3736079)
Affinity DataEC50:  1.00E+3nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499223(CHEMBL3735297)
Affinity DataEC50:  1.26E+3nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499231(CHEMBL3736163)
Affinity DataEC50:  1.59E+3nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499220(CHEMBL3735821)
Affinity DataEC50:  3.16E+3nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499233(CHEMBL3735107)
Affinity DataEC50:  3.98E+3nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50499216(CHEMBL3736345)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50499228(CHEMBL3735458)
Affinity DataEC50: <2.51E+4nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed