Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50006435
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50317209(PF-877423 | (2R)-N-(adamantan-2-yl)-1-ethylpyrroli...)
Affinity DataIC50: 4nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes assessed as conversion of [3H]-cortisone to [3H]-cortisol after 30 mins by scintillation proximit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50499941(CHEMBL3740482)
Affinity DataIC50: 350nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes assessed as conversion of [3H]-cortisone to [3H]-cortisol after 30 mins by scintillation proximit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50499940(CHEMBL3740225)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes assessed as conversion of [3H]-cortisone to [3H]-cortisol after 30 mins by scintillation proximit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed