Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50047162
TargetLysine-specific histone demethylase 1A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151585(CHEMBL3774476)
Affinity DataIC50: 280nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151584(CHEMBL3775613)
Affinity DataIC50: 290nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151583(CHEMBL3774920)
Affinity DataIC50: 320nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151587(CHEMBL3774486)
Affinity DataIC50: 440nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151588(CHEMBL3775735)
Affinity DataIC50: 610nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | trans-2-phe...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | trans-2-phe...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151583(CHEMBL3774920)
Affinity DataIC50: 5.05E+3nMAssay Description:Inhibition of JARID1A (unknown origin) using H3K4me3 peptide substrate preincubated for 5 mins followed by substrate addition by MALDI-TOF mass spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151585(CHEMBL3774476)
Affinity DataIC50: 6.74E+3nMAssay Description:Inhibition of JARID1A (unknown origin) using H3K4me3 peptide substrate preincubated for 5 mins followed by substrate addition by MALDI-TOF mass spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 2(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151583(CHEMBL3774920)
Affinity DataIC50: 7.51E+3nMAssay Description:Inhibition of full length N-terminal His-tagged human LSD2 (1 to 822 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me2 peptide su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151586(CHEMBL3774631)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151584(CHEMBL3775613)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of JARID1A (unknown origin) using H3K4me3 peptide substrate preincubated for 5 mins followed by substrate addition by MALDI-TOF mass spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 2(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151585(CHEMBL3774476)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of full length N-terminal His-tagged human LSD2 (1 to 822 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me2 peptide su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151590(CHEMBL3774901)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 2(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151584(CHEMBL3775613)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of full length N-terminal His-tagged human LSD2 (1 to 822 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me2 peptide su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151585(CHEMBL3774476)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151587(CHEMBL3774486)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151586(CHEMBL3774631)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151585(CHEMBL3774476)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151584(CHEMBL3775613)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151583(CHEMBL3774920)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151587(CHEMBL3774486)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151586(CHEMBL3774631)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151584(CHEMBL3775613)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151583(CHEMBL3774920)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151589(CHEMBL3775045)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | trans-2-phe...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 2(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151586(CHEMBL3774631)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length N-terminal His-tagged human LSD2 (1 to 822 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me2 peptide su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 2(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151587(CHEMBL3774486)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length N-terminal His-tagged human LSD2 (1 to 822 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me2 peptide su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151587(CHEMBL3774486)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of JARID1A (unknown origin) using H3K4me3 peptide substrate preincubated for 5 mins followed by substrate addition by MALDI-TOF mass spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151586(CHEMBL3774631)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of JARID1A (unknown origin) using H3K4me3 peptide substrate preincubated for 5 mins followed by substrate addition by MALDI-TOF mass spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151591(CHEMBL3775421)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed