Report error Found 248 Enz. Inhib. hit(s) with all data for entry = 50047300
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant full length FLAG-tagged KDM5A (unknown origin) expressed in sf9 cells using biotin-H3K4me3 (1 to 21 residues as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant GST-tagged KDM1A (172 to 833 residues) expressed in Escherichia coli C43(DE3) pLysS cells using biotin-H3K4me as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant GST-tagged KDM1A (172 to 833 residues) expressed in Escherichia coli C43(DE3) pLysS cells using biotin-H3K4me as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant GST-tagged KDM1A (172 to 833 residues) expressed in Escherichia coli C43(DE3) pLysS cells using biotin-H3K4me as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of full length human KDM1A expressed in Escherichia coli using biotin-H3K4me1 as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of KDM1A in human THP1 cells assessed as inhibition of CD11b expressing cells incubated for 4 days by DAPI staining based flow cytometryMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using H3K4me3 as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant full length FLAG-tagged KDM5A (unknown origin) expressed in sf9 cells using biotin-H3K4me3 (1 to 21 residues as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant full length FLAG-tagged KDM5A (unknown origin) expressed in sf9 cells using biotin-H3K4me3 (1 to 21 residues as substrate p...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human recombinant KDM1A expressed in Escherichia coli using H3K4me as substrate by peroxidase coupled enzyme assayMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Inhibition of GST-tagged KDM1A (unknown origin) expressed in Escherichia coli BL21-CodonPlus-(DE3)-RIPL cells using dimethyl-Lys-4 H3-21 as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM1A expressed in Escherichia coli using H3K4me2 as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotinylated histone H3 as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli using methylated biotin-H3K9 substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5A in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM4C (1 to 349 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 as substrate preincubated for 10...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5A in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM4C (1 to 349 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 as substrate preincubated for 10...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5A in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5A in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5A in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM4C (1 to 349 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 as substrate preincubated for 10...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5B in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5B (1 to 809 residues) (unknown origin) expressed in Escherichia coli using biotin-H3K4me3 as substrate preincubated for 10 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5B in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5B (1 to 809 residues) (unknown origin) expressed in Escherichia coli using biotin-H3K4me3 as substrate preincubated for 10 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5B in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5B (1 to 809 residues) (unknown origin) expressed in Escherichia coli using biotin-H3K4me3 as substrate preincubated for 10 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged Tev-KDM4C (1 to 366 residues) (unknown origin) using K3K9me3 as substrate preincubated for 10 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged Tev-KDM4C (1 to 366 residues) (unknown origin) using K3K9me3 as substrate preincubated for 10 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5B in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5B in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged Tev-KDM4C (1 to 366 residues) (unknown origin) using K3K9me3 as substrate preincubated for 10 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged Tev-KDM4C (1 to 366 residues) (unknown origin) using K3K9me3 as substrate preincubated for 10 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected sf9 cells using biotin-H3K4me3 as...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM6A (919 to 1401 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 as substrate preincubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM6A (919 to 1401 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 as substrate preincubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant KDM1A expressed in Escherichia coli using biotin-histone H3 as substrate preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant KDM1A expressed in Escherichia coli using biotin-histone H3 as substrate preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant KDM1A expressed in Escherichia coli using biotin-histone H3 as substrate preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant KDM1A expressed in Escherichia coli using biotin-histone H3 as substrate preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5A (unknown origin)More data for this Ligand-Target Pair







3D Structure (crystal)





















