Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50047309
TargetHydroxycarboxylic acid receptor 2(Human)
Catabasis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataEC50:  730nMAssay Description:Activation of GPR109A in human A431 cells assessed as suppression of forskolin-induced cAMP production after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSterol regulatory element-binding protein 2(Human)
Catabasis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50159362(CHEMBL3785912)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of SREBP2 in human HepG2 cells assessed as reduction of PCSK9 secretion after 16 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2017
Entry Details Article
PubMed