Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50047008
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM149712(US8975409, Example 9)
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143197(CHEMBL3759037)
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143192(CHEMBL3758929)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM149709(US8975409, Example 19)
Affinity DataIC50: 5.20nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM149705(US8975409, Example 9(3))
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143201(CHEMBL3759864)
Affinity DataIC50: 6.40nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143203(CHEMBL3759434)
Affinity DataIC50: 8.20nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143206(CHEMBL3759532)
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143202(CHEMBL3758872)
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143200(CHEMBL3758775)
Affinity DataIC50: 9.30nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143198(CHEMBL3758974)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143191(CHEMBL3758214)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143205(CHEMBL3758803)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143195(CHEMBL3759799)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143193(CHEMBL3759551)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143199(CHEMBL3759492)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143194(CHEMBL3758346)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143204(CHEMBL3760061)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143196(CHEMBL3759218)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143203(CHEMBL3759434)
Affinity DataIC50: 500nMAssay Description:Displacement of [33P]-S1P from human S1P2 receptor expressed on CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143203(CHEMBL3759434)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]-S1P from human S1P3 receptor expressed on CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143203(CHEMBL3759434)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]-S1P from human S1P5 receptor expressed on CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143203(CHEMBL3759434)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]-S1P from human S1P4 receptor expressed on CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143203(CHEMBL3759434)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]-S1P from human S1P1 receptor expressed on CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed