Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50047265
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50156370(CHEMBL3793436)
Affinity DataEC50:  0.0620nMAssay Description:Agonist activity at mouse TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50156370(CHEMBL3793436)
Affinity DataEC50:  6.40E+3nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50156371(CHEMBL3794367)
Affinity DataEC50: >100nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50156372(CHEMBL3792938)
Affinity DataEC50: >100nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50160883(CHEMBL3793859)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50160881(CHEMBL3792957)
Affinity DataEC50:  7.80nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50160884(CHEMBL3794424)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50160882(CHEMBL3794111)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50160886(CHEMBL3794442)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50156370(CHEMBL3793436)
Affinity DataEC50:  0.0570nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50161835(CHEMBL3793168)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50161833(CHEMBL3793388)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50161837(CHEMBL3794293)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50161834(CHEMBL3794175)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50161836(CHEMBL3793012)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataIC50: 251nMAssay Description:Agonist activity at TGR5 in human whole blood assessed as inhibition of LPS-induced TNF-alpha releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed