Compile Data Set for Download or QSAR
Report error Found 96 Enz. Inhib. hit(s) with all data for entry = 50047295
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158395(CHEMBL3782037)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158394(CHEMBL3780645)
Affinity DataEC50:  0.400nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158418(CHEMBL3780746)
Affinity DataEC50:  0.460nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158398(CHEMBL3780633)
Affinity DataEC50:  1nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158404(CHEMBL3780373)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158409(CHEMBL3779931)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158418(CHEMBL3780746)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158418(CHEMBL3780746)
Affinity DataEC50:  4nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158395(CHEMBL3782037)
Affinity DataEC50:  4nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158395(CHEMBL3782037)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158394(CHEMBL3780645)
Affinity DataEC50:  5nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158394(CHEMBL3780645)
Affinity DataEC50:  5.90nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...)
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158396(CHEMBL3781773)
Affinity DataEC50:  9nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158401(CHEMBL3780549)
Affinity DataEC50:  9nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158399(CHEMBL3780802)
Affinity DataEC50:  12nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158409(CHEMBL3779931)
Affinity DataEC50:  12nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158395(CHEMBL3782037)
Affinity DataEC50:  13nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158401(CHEMBL3780549)
Affinity DataEC50:  15nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50072394(PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...)
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R1 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158396(CHEMBL3781773)
Affinity DataEC50:  27nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158396(CHEMBL3781773)
Affinity DataEC50:  27nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158418(CHEMBL3780746)
Affinity DataEC50:  28nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158401(CHEMBL3780549)
Affinity DataEC50:  30nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158394(CHEMBL3780645)
Affinity DataEC50:  31nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158404(CHEMBL3780373)
Affinity DataEC50:  32nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158399(CHEMBL3780802)
Affinity DataEC50:  38nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158398(CHEMBL3780633)
Affinity DataEC50:  39nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158532(CHEMBL3781522)
Affinity DataEC50:  51nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158401(CHEMBL3780549)
Affinity DataEC50:  53nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158394(CHEMBL3780645)
Affinity DataIC50: 69nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158532(CHEMBL3781522)
Affinity DataEC50:  87nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158418(CHEMBL3780746)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158418(CHEMBL3780746)
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R1 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158399(CHEMBL3780802)
Affinity DataEC50:  170nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158400(CHEMBL3780191)
Affinity DataEC50:  206nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158399(CHEMBL3780802)
Affinity DataEC50:  249nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158398(CHEMBL3780633)
Affinity DataEC50:  272nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158532(CHEMBL3781522)
Affinity DataEC50:  320nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158394(CHEMBL3780645)
Affinity DataIC50: 324nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R1 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158396(CHEMBL3781773)
Affinity DataEC50:  339nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158400(CHEMBL3780191)
Affinity DataEC50:  350nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158397(CHEMBL3780836)
Affinity DataEC50:  360nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158397(CHEMBL3780836)
Affinity DataEC50:  380nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158400(CHEMBL3780191)
Affinity DataEC50:  780nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetThyrotropin-releasing hormone receptor(Mouse)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158532(CHEMBL3781522)
Affinity DataEC50:  790nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
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